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Keywords: muscarinic
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Biochem Soc Trans (2023) 51 (2): 691–702.
Published: 04 April 2023
... the dopamine-acetylcholine balance hypothesis in light of recent evidence and describes how the Gα i/o coupled muscarinic M 4 receptor acts in opposition to dopamine signaling in the basal ganglia. We highlight how M 4 signaling can ameliorate or exacerbate movement disorders symptoms and physiological...
Biochem Soc Trans (2001) 29 (4): 505–508.
Published: 01 August 2001
...C. J. van Koppen An important regulatory pathway of G-protein-coupled receptors (GPCRs) is the internalization of receptors into the cell interior. To unravel the molecular mechanisms by which GPCRs are internalized, we have studied the internalization of various members of the family of muscarinic...