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Keywords: mouse model
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Biochem Soc Trans (2010) 38 (6): 1715–1721.
Published: 24 November 2010
... attachments. Whereas the link between nCIN and tumorigenesis is becoming more evident, indications have emerged recently that nCIN can suppress tumour formation as well. To understand these paradoxical findings, novel reagents and more sophisticated mouse models are needed. This will provide us with a better...
Biochem Soc Trans (2008) 36 (6): 1233–1238.
Published: 19 November 2008
... using Atp7b −/− mice, as well as advantages and limitations of Atp7b −/− mice as an experimental model for Wilson's disease. 1 email lutsenko@ohsu.edu 7 7 2008 © The Authors Journal compilation © 2008 Biochemical Society 2008 ATP7A ATP7B copper liver mouse model Wilson's...
Biochem Soc Trans (2007) 35 (5): 1005–1008.
Published: 25 October 2007
...). The contributions of individual PKC isoforms can be addressed directly in platelets from knockout mouse models, which are providing key insights into the physiological function of PKC isoform diversity and can be a valuable complimentary approach to more commonly used pharmacological analyses. Using knockout mouse...
Biochem Soc Trans (2007) 35 (2): 231–235.
Published: 20 March 2007
... brian.hemmings@fmi.ch ). 16 12 2006 © 2007 The Biochemical Society 2007 adipocyte differentiation cancer glucose homoeostasis mouse model phosphatase and tensin homologue deleted on chromosome 10 (PTEN) protein kinase B (PKB) The serine/threonine kinase PKB (protein kinase B, also...