..., with the deposition of the EJC (exon junction complex) during splicing resulting in significant modulation of the motile properties of mRNPs in the oocyte cytoplasm [ 10 , 28 ]. Mutations in EJC components appear to favour the overall activity of dynein at the expense of that of kinesin-1 [ 10 ], although...

...Abhrajyoti Ghosh; Sonja-Verena Albers Motility is a common behaviour in prokaryotes. Both bacteria and archaea use flagella for swimming motility, but it has been well documented that structures of the flagellum from these two domains of life are completely different, although they contribute...

...Imogen A. Sparkes Organelle movement in plants cells is extremely dynamic. Movement is driven by the acto-myosin system. Higher plant myosins fall into two classes: classes XI and VIII. Localization studies have highlighted that myosins are present throughout the cytosol, label motile puncta...

... associated with abnormal angiogenesis but the mechanisms are poorly understood. Recent studies show that altering ADMA metabolism in vivo and in vitro modulates the activity of Rho GTPases, key regulators of actin dynamics, endothelial cell motility and angiogenesis. In the present review, we consider...

... A). Individual droplets can switch between these two motility states [ 11 ]. Several intracellular pathogens induce droplet motion ( Figures 1 B and 1 C). The bacterium Chlamydia trachomatis lives inside membrane-bound ‘parasitophorous vacuoles’ and induces the translocation of host lipid droplets...

... 2007 © The Authors Journal compilation © 2008 Biochemical Society 2008 ATP associated with various cellular activities (AAA+) ATP hydrolysis dynein microtubule motility motor protein Dynein is one of the most distant members of the AAA+ (ATPase associated with various cellular...

... for their roles at the centre of dynamic actin reorganization. 1 To whom correspondence should be addressed (email R.H.Insall@bham.ac.uk ). 1 8 2005 © 2005 The Biochemical Society 2005 actin actin-related protein 2/3 complex (Arp2/3 complex) Dictyostelium motility suppressor...

... isoforms of ubiquitous enzymes within flagellate eukaryotes. It was first shown more than 20 years ago that an ability to provide ATP along the length of the axoneme could be important for sperm motility [ 4 ]. Within seawater, sea urchin sperms are spawned into an environment where an adequate...

...M.C. Parrini; M. Matsuda; J. de Gunzburg Pak1 (p21-activated kinase 1) is a key regulator of the actin cytoskeleton, adhesion and cell motility. Such biological roles require a tight spatial and kinetic control of its localization and activity. We summarize here the current knowledge on Pak1...

... involving movement and shape change, such as chemotaxis, cell spreading, phagocytosis and platelet activation. Production of actin filaments underneath the membrane is the driving force for the formation of membrane protrusions and, hence, cell motility. Within this pathway, the Arp2/3 complex...

... at Chancellors Conference Centre, University of Manchester, 1–3 December 2003 19 November 2003 © 2004 Biochemical Society 2004 integrin mitogen-activated protein kinase (MAP kinase) motility p21-activated kinase (PAK) protein kinase A (PKA) Rho GTPase Abbreviations used: ECM...

... 2003 Biochemical Society 2003 cytoskeleton lysophosphatidic acid (LPA) motility phospholipase Rho GTPase Tiam1 Abbreviations used: LPA, lysophosphatidic acid; GPCR, G-protein-coupled receptor; PI 3-kinase, phosphoinositide 3-kinase; EGF, epidermal growth factor; PLD, phospholipase...