... BY) . cryo-EM molecular motor rotary ATPase vacuolar ATPase The rotary ATPase families are membrane-bound molecular motors which act either by hydrolysing ATP to generate a proton gradient or by utilizing an existing proton gradient to energize ATP synthesis. The family consists of the ATP...

... mitochondrial Rho (Miro) mitochondrion mitophagy molecular motor trafficking The brain is only 2% of the body's weight, but it uses 20% of the body's resting energy production. This high level of energy consumption is mainly used to reverse the ion fluxes that underlie action potential signalling...

... Biochemical Society 2012 dynein kinesin microtubule molecular motor optical trap simulation The molecular motor kinesin-1 is a member of the kinesin family of mechanoenzymes that are present in all eukaryotes. It uses the hydrolysis of ATP to produce piconewton forces through chemically...

...Florian Berger; Corina Keller; Melanie J.I. Müller; Stefan Klumpp; Reinhard Lipowsky Intracellular transport is often driven co-operatively by several molecular motors, which may belong to one or several motor species. Understanding how these motors interact and what co-ordinates and regulates...

...Kuniyoshi Kaseda; Andrew D. McAinsh; Robert A. Cross It is clear that the main cellular mission of the molecular motor kinesin-5 (known as Eg5 in vertebrates) is to cross-link antiparallel microtubules and to slide them apart, thus playing a critical role during bipolar spindle formation...

... modulators of channel synthesis and assembly, post-translational processing, various molecular motors and an increasing number of modifying enzymes and molecular anchors. The roles of anchoring proteins, molecular motors and kinases are explored and recent findings on channel internalization and trafficking...

...R.L. Eoff; K.D. Raney Helicases are molecular-motor enzymes that manipulate DNA or RNA during replication, repair, recombination, transcription, translation and processing of nucleic acids. The mechanisms for helicase activity have been studied intensely over the past decade. Recent advances in our...