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1-29 of 29
Keywords: mitogen-activated protein kinase (MAPK)
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Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2015) 43 (5): 1069–1074.
Published: 09 October 2015
... and in disease development. 1 To whom correspondence should be addressed (email e.kiss-toth@sheffield.ac.uk ) . 29 4 2015 © 2015 Authors; published by Portland Press Limited 2015 chronic inflammation disease mitogen-activated protein kinase (MAPK) tribbles The TRIB...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2015) 43 (5): 1104–1107.
Published: 09 October 2015
... © 2015 Authors; published by Portland Press Limited 2015 acute myeloid leukaemia (AML) CCAAT/enhancer binding protein (C/EBP) haematopoiesis mitogen-activated protein kinase (MAPK) tribbles homolog 1 (Trib1) Pseudokinase proteins modulate multiple signalling pathways by interacting...
Articles
Gopika N. Nithianandarajah-Jones, Bettina Wilm, Christopher E.P. Goldring, Jürgen Müller, Michael J. Cross
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2014) 42 (6): 1584–1589.
Published: 17 November 2014
...Gopika N. Nithianandarajah-Jones; Bettina Wilm; Christopher E.P. Goldring; Jürgen Müller; Michael J. Cross Extracellular-signal-regulated kinase 5 (ERK5), also termed big MAPK1 (BMK1), is the most recently discovered member of the mitogen-activated protein kinase (MAPK) family. It is expressed...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2014) 42 (1): 11–24.
Published: 23 January 2014
... within the greater context of the field. 1 email k.y.clark@dundee.ac.uk 26 6 2013 © The Authors Journal compilation © 2014 Biochemical Society 2014 inhibitor of nuclear factor κB kinase (IKK) innate immunity mitogen-activated protein kinase (MAPK) phosphoinositide 3-kinase...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2013) 41 (4): 987–994.
Published: 18 July 2013
... 2013 Ca 2+ /calmodulin-activated serine kinase (CASK) human epidermal growth factor receptor 3 (Her3) kinase suppressor of Ras (KSR) mitogen-activated protein kinase (MAPK) extracellular-signal-regulated kinase pseudokinase Raf 1 email arvin.dar@mssm.edu 11 6 2013...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2012) 40 (1): 230–234.
Published: 19 January 2012
... transcription factor 2 (ATF2) activating transcription factor 7 (ATF7) activator protein 1 (AP-1) c-Jun N-terminal kinase (JNK) mitogen-activated protein kinase (MAPK) p38 Among the ATF (activating transcription factor) family, ATF2 and ATF7 are structurally very similar, especially within the bZIP...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2012) 40 (1): 90–93.
Published: 19 January 2012
... Biochemical Society 2012 Akt/protein kinase B (PKB) cancer metastasis epithelial–mesenchymal transition (EMT) mitogen-activated protein kinase (MAPK) Twist phosphorylation transforming growth factor β receptor signalling (TGFβR signalling) Epithelial and mesenchymal cells are the two major...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2012) 40 (1): 58–66.
Published: 19 January 2012
... gene might present a unique set of challenges to the transcriptional regulatory machinery. 20 6 2011 © The Authors Journal compilation © 2012 Biochemical Society 2012 E26-like kinase 1 (ELK1) FOS immediate-early gene mitogen-activated protein kinase (MAPK) ternary complex...
Articles
Ahmed Lawan, Emma Torrance, Sameer Al-Harthi, Muhannad Shweash, Sulaiman Alnasser, Thikryat Neamatallah, Juliane Schroeder, Robin Plevin
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2012) 40 (1): 235–239.
Published: 19 January 2012
... cancer dual-specificity phosphatase (DUSP) immunity mitogen-activated protein kinase (MAPK) mitogen-activated protein kinase phosphatase 2 (MKP-2) phosphatase proliferation The explosion in the delineation of intracellular kinase signalling pathways in the last 25 years has been exemplified...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2012) 40 (1): 139–146.
Published: 19 January 2012
... a plethora of distinct spatiotemporal response patterns, which may facilitate an effective discrimination between combinations of extracellular cues and lead to different cell-fate decisions [ 2 ]. Akt cross-talk mitogen-activated protein kinase (MAPK) phosphoinositide 3-kinase (PI3K) Ras ©...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2012) 40 (1): 224–229.
Published: 19 January 2012
... Biochemical Society 2012 extracellular-signal-regulated kinase (ERK) high content microscopy mitogen-activated protein kinase (MAPK) mitogen-activated protein kinase/extracellular-signal-regulated kinase kinase (MEK) nuclear accumulation ERK (extracellular-signal-regulated kinase) 1 and 2...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2012) 40 (1): 85–89.
Published: 19 January 2012
...) mitogen-activated protein kinase (MAPK) mitogen-activated protein kinase kinase 4 (MKK4) mitogen-activated protein kinase kinase 7 (MKK7) neurodegeneration Cells have the ability to communicate with each other and modify their behaviour according to changes in their environment. The information...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2011) 39 (2): 684–687.
Published: 22 March 2011
... 2011 Biochemical Society 2011 activating transcription factor 4 (ATF4) acute myeloid leukaemia (AML) cell signalling genome-wide association study (GWAS) mitogen-activated protein kinase (MAPK) tribbles Tribbles (trb) proteins have been discovered and characterized as a key protein...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2010) 38 (5): 1257–1264.
Published: 24 September 2010
... points of study. 1 To whom correspondence should be addressed (email edda.klipp@rz.hu-berlin.de ). 10 3 2010 © The Authors Journal compilation © 2010 Biochemical Society 2010 mitogen-activated protein kinase (MAPK) Saccharomyces cerevisiae signal integration signal...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2010) 38 (4): 1027–1032.
Published: 26 July 2010
... kinase 3 (GSK3) ground state mitogen-activated protein kinase (MAPK) pluripotency signalling Mouse ES (embryonic stem) cells are derived from the ICM (inner cell mass) of the blastocyst-stage embryo [ 1 ]. ES cell derivation can be considered the ‘capture’ of a transient developmental state...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2009) 37 (6): 1254–1259.
Published: 19 November 2009
... m.j.cross@liv.ac.uk ). 5 8 2009 © The Authors Journal compilation © 2009 Biochemical Society 2009 angiogenesis big mitogen-activated protein kinase 1 (BMK1) endothelial cell extracellular-signal-regulated kinase 5 (ERK5) mitogen-activated protein kinase (MAPK) signal transduction...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2009) 37 (4): 824–829.
Published: 22 July 2009
...) corticosteroid mitogen-activated protein kinase (MAPK) steroid theophylline Asthma is a common chronic inflammatory disease and afflicts approx. 300 million people worldwide [ 1 ]. Asthma accounts for ∼1 out of every 250 deaths worldwide and also has profound health care and societal costs in terms...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2009) 37 (1): 237–241.
Published: 20 January 2009
... circumstances, as transporter-like sensors (or ‘transceptors’) upstream of mTOR. 1 email p.m.taylor@dundee.ac.uk 12 9 2008 © The Authors Journal compilation © 2009 Biochemical Society 2009 amino acid transporter general control non-derepressible (GCN) mitogen-activated protein...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2009) 37 (1): 273–277.
Published: 20 January 2009
... Janni.Petersen@manchester.ac.uk 18 11 2008 © The Authors Journal compilation © 2009 Biochemical Society 2009 mitogen-activated protein kinase (MAPK) mitotic commitment nutrient stress Polo kinase target of rapamycin (TOR) yeast In all eukaryotes, SAMRPs (stress-activated MAPK...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2008) 36 (5): 1097–1101.
Published: 19 September 2008
...) and MAPK networks to the activation of MPF to regulate the timing of cell division. 1 email ihagan@picr.man.ac.uk 17 3 2008 © The Authors Journal compilation © 2008 Biochemical Society 2008 mitogen-activated protein kinase (MAPK) mitosis-promoting factor (MPF) mitotic...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2007) 35 (3): 442–445.
Published: 22 May 2007
... by K. Botham and C. Wheeler-Jones (Royal Veterinary College, London, U.K.). chylomicron remnant-like particle cyclo-oxygenase (COX) endothelial cell haem oxygenase-1 (HO-1) mitogen-activated protein kinase (MAPK) prostanoid EC (endothelial cell) dysfunction is characterized...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2006) 34 (5): 842–845.
Published: 25 October 2006
.... Bennett A.M. Mol. Cell. Biol. 2005 25 4792 4803 1 To whom correspondence should be addressed (email Stephen.Keyse@cancer.org.uk ). 25 7 2006 © 2006 The Biochemical Society 2006 binding partner extracellular-signal-regulated kinase (ERK) mitogen-activated protein...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2006) 34 (5): 828–832.
Published: 25 October 2006
... kinase (JNK)-interacting protein (JIP) mitogen-activated protein kinase (MAPK) scaffold protein All the JIP proteins can form homo-oligomers, while JIP2 can also hetero-oligomerize with JIP1 and JIP3 [ 7 , 8 , 10 , 26 ]. X-ray crystallography and mutational analysis have demonstrated that JIP1...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2006) 34 (6): 1018–1023.
Published: 25 October 2006
... innate immune response mitogen-activated protein kinase (MAPK) The MAPKs are components of intracellular signalling pathways that control a vast array of cellular processes, one of which is the innate immune response to infection or tissue injury. The ERK (extracellular-signal-regulated kinase...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2006) 34 (5): 833–836.
Published: 25 October 2006
...) form. The active Ras initiates a cascade that proceeds via sequential phosphorylation and activation of protein kinases, culminating in modulation of the function of multiple substrates in the cell. P, phosphate. growth factor IQGAP1 kinase suppressor of Ras (KSR) mitogen-activated protein...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2006) 34 (5): 837–841.
Published: 25 October 2006
... Society 2006 docking site mitogen-activated protein kinase (MAPK) scaffold protein Ste7 yeast Specificity in cellular signal transduction is achieved by multiple mechanisms. First and foremost, as in all other cellular processes, the pre-eminent mechanism of biochemical specificity...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2005) 33 (5): 1158–1161.
Published: 26 October 2005
... The Biochemical Society 2005 anionic phospholipid β-1,3-glucan cardiolipin (CL) cell wall biogenesis mitochondrion mitogen-activated protein kinase (MAPK) Cardiolipin (CL) is an acidic glycerophospholipid with a unique dimeric structure consisting of four fatty acyl chains. It is ubiquitous...
Articles
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2003) 31 (6): 1171–1177.
Published: 01 December 2003
... cells. VEGF (vascular endo- thelial growth factor A), and its major signalling receptor Key words: angiogenesis, Flt1, kinase-insert-domain-containing receptor (KDR), mitogen- activated protein kinase (MAPK), survival, vascular endothelial growth factor (VEGF). Abbreviations used: eNOS, endothelial...
Articles
M. M. Manson, K. A. Holloway, L. M. Howells, E. A. Hudson, S. M. Plummer, M. S. Squires, S. A. Prigent
Journal:
Biochemical Society Transactions
Biochem Soc Trans (2000) 28 (2): 7–12.
Published: 01 February 2000
...-dependent kinase apoptosis curcumin epigallocatechin gallate (EGCG) mitogen-activated protein kinase (MAPK) nuclear factor kB (NF-kB) Chemoprotection Modulation of signal-transduction pathways by chemopreventive agents M. M. Manson K. A. Holloway*, L. M. Howelk*, E. A. Hudson*, S. M. Plummer...