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Keywords: mitogen-activated protein kinase (MAPK)
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Articles
Biochem Soc Trans (2015) 43 (5): 1104–1107.
Published: 09 October 2015
... e109530 10.1371/journal.pone.0109530 25329475 acute myeloid leukaemia (AML) CCAAT/enhancer binding protein (C/EBP) haematopoiesis mitogen-activated protein kinase (MAPK) tribbles homolog 1 (Trib1) The importance of Trib1 in leukaemogenesis and haematopoiesis has been increasingly...
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Biochem Soc Trans (2015) 43 (5): 1069–1074.
Published: 09 October 2015
... Authors; published by Portland Press Limited 2015 chronic inflammation disease mitogen-activated protein kinase (MAPK) tribbles TRIB modulate several components of significant inflammatory signalling pathways that are triggered by ligands of toll/interleukin 1 (IL-1)-receptors (IL1Rs...
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Biochem Soc Trans (2014) 42 (6): 1584–1589.
Published: 17 November 2014
...Gopika N. Nithianandarajah-Jones; Bettina Wilm; Christopher E.P. Goldring; Jürgen Müller; Michael J. Cross Extracellular-signal-regulated kinase 5 (ERK5), also termed big MAPK1 (BMK1), is the most recently discovered member of the mitogen-activated protein kinase (MAPK) family. It is expressed...
Articles
Biochem Soc Trans (2014) 42 (1): 11–24.
Published: 23 January 2014
... The Authors Journal compilation © 2014 Biochemical Society 2014 inhibitor of nuclear factor κB kinase (IKK) innate immunity mitogen-activated protein kinase (MAPK) phosphoinositide 3-kinase (PI3K) salt-inducible kinase (SIK) Toll-like receptor (TLR) The innate immune system is our first...
Articles
Biochem Soc Trans (2013) 41 (4): 987–994.
Published: 18 July 2013
... The Authors Journal compilation © 2013 Biochemical Society 2013 Ca 2+ /calmodulin-activated serine kinase (CASK) human epidermal growth factor receptor 3 (Her3) kinase suppressor of Ras (KSR) mitogen-activated protein kinase (MAPK) extracellular-signal-regulated kinase pseudokinase Raf...
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Biochem Soc Trans (2012) 40 (1): 230–234.
Published: 19 January 2012
... development and their potential functions in tumour formation. © The Authors Journal compilation © 2012 Biochemical Society 2012 activating transcription factor 2 (ATF2) activating transcription factor 7 (ATF7) activator protein 1 (AP-1) c-Jun N-terminal kinase (JNK) mitogen-activated protein...
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Biochem Soc Trans (2012) 40 (1): 90–93.
Published: 19 January 2012
... in response to apoptotic stimuli. Adapted from [ 20 ] with permission. Akt/protein kinase B (PKB) cancer metastasis epithelial–mesenchymal transition (EMT) mitogen-activated protein kinase (MAPK) Twist phosphorylation transforming growth factor β receptor signalling (TGFβR signalling...
Articles
Biochem Soc Trans (2012) 40 (1): 58–66.
Published: 19 January 2012
...) FOS immediate-early gene mitogen-activated protein kinase (MAPK) ternary complex factor (TCF) FOS was initially identified as a gene that is very rapidly induced upon treatment of mammalian cells with serum or growth factors without the need for new protein synthesis [ 1 – 3...
Articles
Biochem Soc Trans (2012) 40 (1): 235–239.
Published: 19 January 2012
... progression that are distinct from those of other DUSPs. However, many functions for MKP-2 still await to be characterized. cancer dual-specificity phosphatase (DUSP) immunity mitogen-activated protein kinase (MAPK) mitogen-activated protein kinase phosphatase 2 (MKP-2) phosphatase proliferation...
Articles
Biochem Soc Trans (2012) 40 (1): 139–146.
Published: 19 January 2012
... 5 2011 © The Authors Journal compilation © 2012 Biochemical Society 2012 Akt cross-talk mitogen-activated protein kinase (MAPK) phosphoinositide 3-kinase (PI3K) Ras A cell in an organism is immersed in an ocean of growth factors and hormones, yet how signalling networks...
Articles
Biochem Soc Trans (2012) 40 (1): 224–229.
Published: 19 January 2012
... Society 2012 extracellular-signal-regulated kinase (ERK) high content microscopy mitogen-activated protein kinase (MAPK) mitogen-activated protein kinase/extracellular-signal-regulated kinase kinase (MEK) nuclear accumulation ERK (extracellular-signal-regulated kinase) 1 and 2 (referred...
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Articles
Biochem Soc Trans (2011) 39 (2): 684–687.
Published: 22 March 2011
.... Kiss-Toth E. Tribbles-1, a mitogen activated protein kinase (MAPK) scaffold regulates inflammation in vascular smooth muscle cells (VSMC) and atherosclerosis Heart 2005 91 A15 A15 39 Kiss-Toth E. Wyllie D.H. Holland K. Marsden L. Jozsa V. Oxley K.M. Polgar T...
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Biochem Soc Trans (2010) 38 (5): 1257–1264.
Published: 24 September 2010
... points of study. 1 To whom correspondence should be addressed (email edda.klipp@rz.hu-berlin.de ). 10 3 2010 © The Authors Journal compilation © 2010 Biochemical Society 2010 mitogen-activated protein kinase (MAPK) Saccharomyces cerevisiae signal integration signal...
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Biochem Soc Trans (2010) 38 (4): 1027–1032.
Published: 26 July 2010
... be addressed (email ags39@cam.ac.uk ). 8 1 2010 © The Authors Journal compilation © 2010 Biochemical Society 2010 embryonic stem cell glycogen synthase kinase 3 (GSK3) ground state mitogen-activated protein kinase (MAPK) pluripotency signalling Mouse ES (embryonic stem) cells...
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Biochem Soc Trans (2009) 37 (6): 1254–1259.
Published: 19 November 2009
... angiogenesis big mitogen-activated protein kinase 1 (BMK1) endothelial cell extracellular-signal-regulated kinase 5 (ERK5) mitogen-activated protein kinase (MAPK) signal transduction Figure 1 Structure and function of ERK5 The ERK5 protein consists of 816 amino acids and contains a kinase...
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Biochem Soc Trans (2009) 37 (4): 824–829.
Published: 22 July 2009
...) corticosteroid mitogen-activated protein kinase (MAPK) steroid theophylline Asthma is a common chronic inflammatory disease and afflicts approx. 300 million people worldwide [ 1 ]. Asthma accounts for ∼1 out of every 250 deaths worldwide and also has profound health care and societal costs in terms...
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Biochem Soc Trans (2009) 37 (1): 237–241.
Published: 20 January 2009
... circumstances, as transporter-like sensors (or ‘transceptors’) upstream of mTOR. 1 email p.m.taylor@dundee.ac.uk 12 9 2008 © The Authors Journal compilation © 2009 Biochemical Society 2009 amino acid transporter general control non-derepressible (GCN) mitogen-activated protein...
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Biochem Soc Trans (2009) 37 (1): 273–277.
Published: 20 January 2009
... Janni.Petersen@manchester.ac.uk 18 11 2008 © The Authors Journal compilation © 2009 Biochemical Society 2009 mitogen-activated protein kinase (MAPK) mitotic commitment nutrient stress Polo kinase target of rapamycin (TOR) yeast Rapamycin inhibition of TOR signalling activates...
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Biochem Soc Trans (2008) 36 (5): 1097–1101.
Published: 19 September 2008
...) and MAPK networks to the activation of MPF to regulate the timing of cell division. 1 email ihagan@picr.man.ac.uk 17 3 2008 © The Authors Journal compilation © 2008 Biochemical Society 2008 mitogen-activated protein kinase (MAPK) mitosis-promoting factor (MPF) mitotic...
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Biochem Soc Trans (2007) 35 (3): 442–445.
Published: 22 May 2007
... with pharmacological intervention to limit endothelial dysfunction and cardiovascular disease. chylomicron remnant-like particle cyclo-oxygenase (COX) endothelial cell haem oxygenase-1 (HO-1) mitogen-activated protein kinase (MAPK) prostanoid EC (endothelial cell) dysfunction is characterized...
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Biochem Soc Trans (2006) 34 (5): 833–836.
Published: 25 October 2006
... is necessary to validate this premise. growth factor IQGAP1 kinase suppressor of Ras (KSR) mitogen-activated protein kinase (MAPK) mitogen-activated protein kinase/extracellular-signal-regulated kinase kinase (MEK) scaffold Signal transduction networks enable alterations...
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Biochem Soc Trans (2006) 34 (5): 837–841.
Published: 25 October 2006
... Society 2006 docking site mitogen-activated protein kinase (MAPK) scaffold protein Ste7 yeast Specificity in cellular signal transduction is achieved by multiple mechanisms. First and foremost, as in all other cellular processes, the pre-eminent mechanism of biochemical specificity...
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Biochem Soc Trans (2006) 34 (5): 828–832.
Published: 25 October 2006
... kinase (JNK)-interacting protein (JIP) mitogen-activated protein kinase (MAPK) scaffold protein All the mammalian JIP proteins are highly expressed in brain [ 6 – 10 ]. JIP1 and JIP2 proteins are also highly expressed in pancreatic β-cells [ 7 , 14 ], with lower levels of JIP1 present...
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Biochem Soc Trans (2006) 34 (6): 1018–1023.
Published: 25 October 2006
... protein kinase (MAPK) The MAPKs are components of intracellular signalling pathways that control a vast array of cellular processes, one of which is the innate immune response to infection or tissue injury. The ERK (extracellular-signal-regulated kinase), JNK (c-Jun N-terminal kinase) and p38 MAPK...
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Biochem Soc Trans (2005) 33 (5): 1158–1161.
Published: 26 October 2005
...-glucan cardiolipin (CL) cell wall biogenesis mitochondrion mitogen-activated protein kinase (MAPK) Cardiolipin (CL) is an acidic glycerophospholipid with a unique dimeric structure consisting of four fatty acyl chains. It is ubiquitous in eukaryotes and primarily found in the mitochondrial...
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Biochem Soc Trans (2003) 31 (6): 1171–1177.
Published: 01 December 2003
... of Essex, Colchester, 2–4 July 2003 10 June 2003 © 2003 Biochemical Society 2003 angiogenesis Flt1 kinase-insert-domain-containing receptor (KDR) mitogen-activated protein kinase (MAPK) survival vascular endothelial growth factor (VEGF) Abbreviations used: eNOS...
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Biochem Soc Trans (2000) 28 (2): 7–12.
Published: 01 February 2000
...-dependent kinase apoptosis curcumin epigallocatechin gallate (EGCG) mitogen-activated protein kinase (MAPK) nuclear factor kB (NF-kB) Chemoprotection Modulation of signal-transduction pathways by chemopreventive agents M. M. Manson K. A. Holloway*, L. M. Howelk*, E. A. Hudson*, S. M. Plummer...