... have the capacity to both divide through mitochondrial fission and coalesce through mitochondrial fusion. Mitochondrial dynamics, the balance between fission and fusion, regulate many cellular functions, including innate immune pathways in macrophages. In these cells, mitochondrial fission has...

... mitochondrial biogenesis mitochondrial dynamics © 2017 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2017 26 5 2017 11 7 2017 13 7 2017 Correspondence: Angelika B. Harbauer ( angelika.harbauer@childrens.harvard.edu ) The total...

...-anchored mitochondrial fission factor (Mff) and N-terminally anchored mitochondrial dynamics proteins of 49 and 51 kDa (MiD49 and MiD51) were additionally identified to recruit Drp1 to mitochondria [ 39 – 42 ]. Further studies showed that Mff and MiDs are the bona fide receptors, whereas Fis1 has little...

... and tensin homologue (PTEN)-induced putative kinase 1], lead to clinically similar early-onset Parkinsonian syndromes. PINK1 and Parkin cooperate within a conserved pathway to preserve mitochondrial quality through the regulation of a variety of processes, including mitochondrial dynamics, transport...

..., aggregated proteins or dysfunctional mitochondria. This is considered to counteract the development of a number of neurodegenerative disorders and aging. Here we review the role of mitophagy and mitochondrial dynamics in ensuring quality control of mitochondria. In particular, we provide possible...

... The Authors Journal compilation © 2011 Biochemical Society 2011 aging cell death mitochondrial dynamics mitochondrial fission mitochondrial fusion Saccharomyces cerevisiae Mitochondria are semi-autonomous organelles that contain their own genome [mtDNA (mitochondrial DNA)], encoding...

... Biochemical Society 2010 clueless cytoskeleton FRIENDLY mitochondrial dynamics mitophagy Parkin 1 email david.logan@usask.ca 14 12 2009 The discovery of mitochondria cannot be attributed to a single person, because many of the granular bodies observed by cytologists...