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Keywords: mitochondrial DNA (mtDNA)
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Articles
Biochem Soc Trans (2013) 41 (5): 1298–1304.
Published: 23 September 2013
...-related disease in each new generation. 1 To whom correspondence should be addressed (email j.f.allen@qmul.ac.uk ). 4 6 2013 © 2013 The Authors 2013 CoRR hypothesis female germline mitochondrial DNA (mtDNA) mitochondrial transcription promitochondrion Mitochondria...
Articles
Biochem Soc Trans (2008) 36 (5): 930–934.
Published: 19 September 2008
... ). 8 5 2008 © The Authors Journal compilation © 2008 Biochemical Society 2008 diabetes lipotoxicity mitochondrial DNA (mtDNA) oxidative stress pancreatic β-cell reactive oxygen species (ROS) Pancreatic β-cells are poised to sense glucose and other nutrient secretagogues...
Articles
Biochem Soc Trans (2007) 35 (5): 1232–1235.
Published: 25 October 2007
..., cell death is observed in the affected region. Future work will involve unravelling the connection between the accumulation of high levels of mtDNA mutations and neurodegeneration both in normal aging and in neurodegenerative disease. mitochondrial DNA (mtDNA) mitochondrial DNA mutation...
Articles
Biochem Soc Trans (2006) 34 (5): 824–827.
Published: 25 October 2006
... in the aetiology of late onset diabetes, elucidating the respective contribution of mtDNA mutations and ROS generation will represent a major challenge. © 2006 The Biochemical Society 2006 cybrid diabetes insulin secretion mitochondrial DNA (mtDNA) oxidative stress pancreatic β-cell...