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Keywords: migration
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Biochem Soc Trans (2015) 43 (3): 482–488.
Published: 01 June 2015
... to the C-terminal domain or the extracellular loops of Cx43 and thus are likely to function by different means. However, both block channel function and have been shown to enhance cell migration rates. In recent years, non-channel functions have emerged for Cx43, many of which are linked to cytoskeletal...
Biochem Soc Trans (2015) 43 (3): 315–321.
Published: 01 June 2015
... synapse (IS) migration super resolution localization microscopy T-cells travel huge distances in the blood and the lymphatics, undergoing thousands of transient interactions with antigen presenting cells (APCs) each day. To do this, T-cells migrate, relying on coordination of actin retrograde...
Biochem Soc Trans (2014) 42 (6): 1490–1497.
Published: 17 November 2014
... that PKCs regulate the production of inflammatory cytokines and the cytotoxic responses of various T-cell subsets. Central to the T-cell immune response is a requirement to migrate to various organs and tissues in search of pathogens and micro-organisms. T-cell migration is guided by specific sets...
Biochem Soc Trans (2012) 40 (6): 1398–1403.
Published: 21 November 2012
... roles in tumour cell migration, invasion, proliferation, communication with stromal cells and the development of drug resistance. As a consequence, Rab proteins may be novel potential candidates for the development of anticancer drugs and, in this context, the preliminary results obtained...
Biochem Soc Trans (2012) 40 (1): 251–256.
Published: 19 January 2012
... of tumour cell invasion and migration. Several oncogenes can stimulate ERK5 activity, and protein levels are increased by a novel amplification at chromosome locus 17p11 and by down-regulation of the microRNAs miR-143 and miR-145 . Together, these finding underscore the case for further investigation...
Biochem Soc Trans (2011) 39 (2): 563–567.
Published: 22 March 2011
...Dale Powner; Petra M. Kopp; Susan J. Monkley; David R. Critchley; Fedor Berditchevski Tetraspanin CD9 is associated with integrin adhesion receptors and it was reported that CD9 regulates integrin-dependent cell migration and invasion. Pro- and anti-migratory effects of CD9 have been linked...
Biochem Soc Trans (2009) 37 (5): 961–965.
Published: 21 September 2009
... cytoplasmic dynein [ 4 ]. Before this study, dynein-driven ER movement had only been seen in the fungus Ustilago maydis [ 19 ], and in mammalian and amphibian eggs [ 20 – 23 ], where dynein also drives pro-nuclear migration [ 23 , 24 ]. Interestingly, although kinesin-1 is present on Xenopus egg and early...
Biochem Soc Trans (2007) 35 (5): 1377–1378.
Published: 25 October 2007
... that lycopene inhibited PDGF-BB (platelet-derived growth factor-BB)-induced signalling and cell migration in human cultured skin fibroblasts through a novel mechanism of action, i.e. direct binding to PDGF-BB. Trapping of PDGF by lycopene also compromised melanoma-induced fibroblast migration and attenuated...
Biochem Soc Trans (2007) 35 (5): 1114–1118.
Published: 25 October 2007
...R. David; F.M. Marelli-Berg Migration of primed T-cells to the antigenic site is an essential event in the development of effective immunity. This process is tightly regulated in order to ensure efficient and specific responses. Most studies have focused on non-specific mediators of T-cell...
Biochem Soc Trans (2005) 33 (4): 694–697.
Published: 01 August 2005
... the normal maintenance of this tissue: differentiation, migration, proliferation and apoptosis. Indeed, APC is involved in the regulation of β-catenin and it also is an important regulator of the cytoskeleton. Thus mutations in APC lead to the accumulation of β-catenin, which causes changes...
Biochem Soc Trans (2004) 32 (1): 97–102.
Published: 01 February 2004
... keratinocytes at the wound margin for re-epithelialization. Together, these observations reveal that PPARβ takes on multiple roles and contributes favourably to the process of wound closure. apoptosis inflammation keratinocyte migration peroxisome-proliferator-activated receptor (PPAR) wound repair...
Biochem Soc Trans (2003) 31 (1): 90–93.
Published: 01 February 2003
...-mail peter.parker@cancer.org.uk ). Signalling the Future, a Biochemical Society-sponsored meeting held at University of Liverpool, Liverpool, 4–6 September 2002 6 September 2002 Copyright 2003 Biochemical Society 2003 adherence migration phosphorylation Abbreviations used: ERM...
Biochem Soc Trans (2000) 28 (2): 199–202.
Published: 01 February 2000
...) mesenchyme and the maternal decidual stroma beneath. From the periphery of these columns, large numbers of trophoblast cells detach, migrate through the decidua and eventually colonize and transform maternal arteries. In this way the placenta increases and gives priority to the maternal blood supply...