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Keywords: microscopy
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Biochem Soc Trans (2021) 49 (5): 2123–2131.
Published: 08 September 2021
... Press and the Biochemical Society. dynamics microscopy p53 signaling single cell With improvements in techniques for the imaging and tracking of single living cells over long timescales, studies over the past two decades have found that the dynamics of cellular signaling pathways, i.e...
Biochem Soc Trans (2018) 46 (3): 729–740.
Published: 05 June 2018
...Lucien E. Weiss; Tal Naor; Yoav Shechtman The structural organization and dynamics of DNA are known to be of paramount importance in countless cellular processes, but capturing these events poses a unique challenge. Fluorescence microscopy is well suited for these live-cell investigations...
Biochem Soc Trans (2017) 45 (5): 1077–1085.
Published: 25 August 2017
.... Understanding how PRRs signal is of critical importance due to their potential as therapeutic targets to ameliorate symptoms of inflammatory diseases. The recent advances in microscopy, such as the discovery of fluorescent proteins and the breaking of the diffraction limit of light, offer a unique opportunity...
Biochem Soc Trans (2009) 37 (4): 914–917.
Published: 22 July 2009
... electrophoresis, these strands are pulled out into the agarose, forming a tail which, when stained with a fluorescent dye, can be analysed by fluorescence microscopy. The intensity of this tail reflects the amount of DNA damage sustained. Despite being such an established and widely used assay, there are still...
Biochem Soc Trans (2008) 36 (4): 749–753.
Published: 22 July 2008
... bacteria as ‘bags of DNA and proteins’, relatively little has been learnt about how they organize their life processes within cells. The mistaken perception of bacteria cells as unstructured systems arose partly because of the difficulty of performing studies by light microscopy due to their small size...
Biochem Soc Trans (2003) 31 (5): 1020–1027.
Published: 01 October 2003
...D.S. Lidke; P. Nagy; B.G. Barisas; R. Heintzmann; J.N. Post; K.A. Lidke; A.H.A. Clayton; D.J. Arndt-Jovin; T.M. Jovin We report the implementation and exploitation of fluorescence polarization measurements, in the form of anisotropy fluorescence lifetime imaging microscopy (rFLIM) and energy...