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Journal: Biochemical Society Transactions
Biochem Soc Trans (2020) 48 (2): 411–418.
Published: 13 March 2020
... inhibitor impaired BMP4-mediated LSC protection against TKIs. Altogether, data based on various studies including ours, indicate that BMP targeting could eliminate leukemic cells within a protective bone marrow microenvironment to efficiently impact residual resistance or persistence of LSCs in myeloid...