... tissue is required to help us understand these metabolic diseases and their regulatory processes. Recently, extracellular vesicles (EVs) have been identified as novel intercellular vectors with a wide range of regulatory functions. The miRNAs carried by EVs participate in the regulation of white adipose...

...-induced putative kinase 1 (PINK1)–Pakin activates protein synthesis on damaged mitochondria to maintain the organelle homeostasis and activity. We also summarize some recent progress on miRNAs' regulation on mitochondrial biogenesis. Correspondence: Hong Xu ( hong.xu@nih.gov ) 10 3 2016 30...

...Daniel R. Hogg; Lorna W. Harries miRNAs are small non-coding regulators of gene expression that are estimated to regulate over 60% of all human genes. Each miRNA can target multiple mRNA targets and as such, miRNAs are responsible for some of the ‘fine tuning’ of gene expression and are implicated...

...Divya Vashisht; Michael D. Nodine Plant miRNAs are short non-coding RNAs that mediate the repression of hundreds of genes. The basic plant body plan is established during early embryogenesis, and recent results have demonstrated that miRNAs play pivotal roles during both embryonic pattern formation...

... methylation miRNA RNA-induced silencing complex (RISC) siRNA The ability to process double-stranded RNA into small 21–28 nt fragments by an RNaseIII-based enzyme called Dicer [or Dicer-like (DCL)] is widespread among eukaryotic cells. The products of cleavage, termed siRNA ( s hort i nterfering...