...-ND) . antibiotics biosynthesis drug discovery and design metabolic engineering Antimicrobial-resistant (AMR) infections pose a serious threat to society [ 1 ], driving the need to discover and develop new antimicrobial molecules. Promising sources of such antimicrobials are naturally...

... or oleaginous yeasts, or from metabolically engineered microbial cell factories. Figure drawn using Biorender software. Figure 3. Natural and engineered metabolic pathways to biofuels. Schematic diagram of natural and engineered pathways to biofuels and biofuel precursors in microbial platforms. Note...

... Jawed et al. [ 18 ] biofuel butanol Escherichia coli metabolic engineering Butanol or butyl alcohol, a 4-carbon alcohol with the chemical formula C 4 H 9 OH, is normally synthesized chemically from propylene or acetaldehyde via oxo or aldol processes, respectively. Butanol can...

...Christopher J. Robinson; Jonathan Tellechea-Luzardo; Pablo Carbonell; Adrian J. Jervis; Cunyu Yan; Katherine A. Hollywood; Mark S. Dunstan; Andrew Currin; Eriko Takano; Nigel S. Scrutton Metabolic engineering technologies have been employed with increasing success over the last three decades...

... reporter chemoenzymatic labelling glycobiology glycosylation metabolic engineering Glycans play crucial roles in a diversity of cellular processes. For example, glycoproteins are essential mediators of cell–cell and cell–matrix interactions, they are involved in cell recognition and signalling...

... by Portland Press Limited on behalf of the Biochemical Society 2020 butanol metabolic engineering renewable resources The world is now facing increasing energy scarcity and escalating environmental problems. Consequently, finding economically viable green alternatives to fossil fuels has...

... as they can be directly incorporated into the current fuel infrastructure without the need for reconstructing the pre-existing set-up rendering them economically viable. Multiple metabolic engineering approaches have been used for rewiring microbes to improve existing or develop newly programmed cells capable...

... 2016 The Author(s) 2016 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . biocatalysis fine chemicals metabolic engineering synthetic biology systems biology...

... be addressed to either author (email drmscaife@gmail.com or as25@cam.ac.uk ). 12 2 2016 © 2016 The Author(s). published by Portland Press Limited on behalf of the Biochemical Society 2016 Chlamydomonas reinhardtii industrial biotechnology metabolic engineering meta data rational...

...Oliver Hädicke; Steffen Klamt Cofactor engineering has been long identified as a valuable tool for metabolic engineering. Besides interventions targeting the pools of redox cofactors, many studies addressed the adenosine pools of microorganisms. In this mini-review, we discuss interventions...

... discuss metabolic engineering strategies specifically targeting energy metabolism as a strategy for yield enhancement. 1 To whom correspondence should be addressed (email fernie@mpimp-golm.mpg.de ). 3 6 2005 © 2005 The Biochemical Society 2005 crop yield energy metabolism...