... into metabolic engineering pipelines offers great opportunities to streamline design and discover control systems for improved production of high-value chemicals. Figure 1. Applications areas of machine learning in dynamic pathway engineering: retrosynthesis, biosensor design, and circuit architecture...

... discovery and design metabolic engineering In the context of NP biosynthesis in E. coli , metabolic engineering has been used to build chassis strains such as HM0079 and BAP1, that are optimized to support the synthesis of complex NPs by expressing phosphopantetheine transferase, an enzyme crucial...

... BY) . biocatalysts biofuels metabolic engineering microbiology synthetic biology Since the industrial revolution, the use of fossilised biomass for energy and chemicals has altered the natural carbon (C) cycle, with major impacts now felt worldwide [ 1 ]. Liquid transport fuels are a convenient form...

...@icgeb.res.in ) 4 11 2021 22 2 2022 15 3 2022 © 2022 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2022 biofuel butanol Escherichia coli metabolic engineering Butanol or butyl alcohol, a 4-carbon alcohol with the chemical...

...Christopher J. Robinson; Jonathan Tellechea-Luzardo; Pablo Carbonell; Adrian J. Jervis; Cunyu Yan; Katherine A. Hollywood; Mark S. Dunstan; Andrew Currin; Eriko Takano; Nigel S. Scrutton Metabolic engineering technologies have been employed with increasing success over the last three decades...

... reporter chemoenzymatic labelling glycobiology glycosylation metabolic engineering Glycans play crucial roles in a diversity of cellular processes. For example, glycoproteins are essential mediators of cell–cell and cell–matrix interactions, they are involved in cell recognition and signalling...

... 17 8 2020 © 2020 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2020 butanol metabolic engineering renewable resources The world is now facing increasing energy scarcity and escalating environmental problems. Consequently, finding...

... as they can be directly incorporated into the current fuel infrastructure without the need for reconstructing the pre-existing set-up rendering them economically viable. Multiple metabolic engineering approaches have been used for rewiring microbes to improve existing or develop newly programmed cells capable...

... the Creative Commons Attribution License 4.0 (CC BY) . biocatalysis fine chemicals metabolic engineering synthetic biology systems biology The Manchester University Synthetic Biology Research Centre (SBRC), SYNBIOCHEM ( http://synbiochem.co.uk ), is focused on delivering Synthetic Biology...

... be addressed to either author (email drmscaife@gmail.com or as25@cam.ac.uk ). 12 2 2016 © 2016 The Author(s). published by Portland Press Limited on behalf of the Biochemical Society 2016 Chlamydomonas reinhardtii industrial biotechnology metabolic engineering meta data rational...

...Oliver Hädicke; Steffen Klamt Cofactor engineering has been long identified as a valuable tool for metabolic engineering. Besides interventions targeting the pools of redox cofactors, many studies addressed the adenosine pools of microorganisms. In this mini-review, we discuss interventions...

... discuss metabolic engineering strategies specifically targeting energy metabolism as a strategy for yield enhancement. 1 To whom correspondence should be addressed (email fernie@mpimp-golm.mpg.de ). 3 6 2005 © 2005 The Biochemical Society 2005 crop yield energy metabolism...