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Biochem Soc Trans (2022) 50 (5): 1527–1539.
Published: 16 September 2022
...Rogério Lopes dos Santos; Clément Campillo Cell shape changes that are fuelled by the dynamics of the actomyosin cytoskeleton control cellular processes such as motility and division. However, the mechanisms of interplay between cell membranes and actomyosin are complicated to decipher...
Biochem Soc Trans (2022) 50 (1): 1–11.
Published: 28 February 2022
... membranes phospholipids William (Bill) EM Lands was a Biological Chemist born in 1930 in Chillilcothe, Missouri. Following a BS in Chemistry in Michigan, a PhD in Biological Chemistry from Illinois, and one year as Post Doc Fellow in California Institute of Technology, he spent 25 years on faculty...
Biochem Soc Trans (2021) 49 (3): 1457–1465.
Published: 22 June 2021
... of Aβ are believed to be the major cause of synaptic dysfunction in AD brain and their cytotoxic mechanisms have been proposed to involve interactions with cell membranes. In this review, we discuss our solid-state nuclear magnetic resonance (ssNMR) studies of Aβ interactions with model membranes...
Biochem Soc Trans (2021) 49 (1): 455–465.
Published: 25 January 2021
...Pratima Verma; Shraddha Gandhi; Kusum Lata; Kausik Chattopadhyay The integrity of the plasma membranes is extremely crucial for the survival and proper functioning of the cells. Organisms from all kingdoms of life employ specialized pore-forming proteins and toxins (PFPs and PFTs) that perforate...
Biochem Soc Trans (2020) 48 (6): 2721–2728.
Published: 18 December 2020
...Agata Nawrotek; Mahel Zeghouf; Jacqueline Cherfils Small GTPases, in association with their GEFs, GAPs and effectors, control major intracellular processes such as signal transduction, cytoskeletal dynamics and membrane trafficking. Accordingly, dysfunctions in their biochemical properties...
Biochem Soc Trans (2019) 47 (5): 1291–1305.
Published: 28 October 2019
...David Barneda; Sabina Cosulich; Len Stephens; Phillip Hawkins The phosphoinositide (PIPn) family of signalling phospholipids are central regulators in membrane cell biology. Their varied functions are based on the phosphorylation pattern of their inositol ring, which can be recognized by selective...
Biochem Soc Trans (2019) 47 (3): 919–932.
Published: 13 May 2019
...Sarah J. Routledge; John A. Linney; Alan D. Goddard Biological membranes form the boundaries to cells. They are integral to cellular function, retaining the valuable components inside and preventing access of unwanted molecules. Many different classes of molecules demonstrate disruptive properties...
Biochem Soc Trans (2018) 46 (4): 871–875.
Published: 19 July 2018
...Jen Vanderhoven; Jeffrey Green; Gavin H. Thomas The ∼1300 academic and industry members of the BBSRC (Biotechnology and Biological Sciences Research Council) Network in Industrial Biotechnology and Bioenergy (NIBB) Crossing Biological Membranes Network (CBMNet) are motivated to explore how...
Biochem Soc Trans (2018) 46 (2): 379–389.
Published: 14 March 2018
...Tamako Nishimura; Nobuhiro Morone; Shiro Suetsugu Lipid membranes are structural components of cell surfaces and intracellular organelles. Alterations in lipid membrane shape are accompanied by numerous cellular functions, including endocytosis, intracellular transport, and cell migration. Proteins...
Biochem Soc Trans (2017) 45 (4): 999–1006.
Published: 14 July 2017
...Jonas Franz; Marco Tarantola; Christoph Riethmüller Tetraspanins are ubiquitous membrane proteins that induce local membrane curvature and hence co-ordinate cell-to-cell contacts. This review highlights their role in inflammation, which requires control of the nano-architecture of attachment sites...
Biochem Soc Trans (2017) 45 (2): 287–295.
Published: 13 April 2017
.... Key findings included the discovery that L-forms use an unusual blebbing, or tubulation and scission mechanism to proliferate. This mechanism is completely independent of the normal FtsZ-based division machinery and seems to require only an increased rate of membrane synthesis, leading to an increased...
Biochem Soc Trans (2016) 44 (2): 479–485.
Published: 11 April 2016
... Optic Atrophy-1 (OPA1), and by this association to maintain mitochondrial morphology, support respiratory chain function, uphold mitochondrial membrane potential, decrease reactive oxygen species production, and inhibit cell death induced by UV irradiation and TNF-α factor [ 14 ]. PA transfer in yeast...