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Keywords: membrane trafficking
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Articles
Biochem Soc Trans (2019) 47 (2): 639–650.
Published: 05 March 2019
... are trafficked to their target destinations via membrane-bound intermediaries. During bone resorption, membrane trafficking must be tightly regulated to sustain the structural and functional polarity of the osteoclasts’ membrane domains. Of these, the ruffled border (RB) is most characteristic, functioning...
Articles
Biochem Soc Trans (2018) 46 (5): 1055–1062.
Published: 21 September 2018
... BY) . EGF receptor intraluminal vesicle membrane contact site membrane trafficking multivesicular body ESCRT (Endosomal Sorting Complex Required for Transport)-dependent sorting of ubiquitinated EGF (epidermal growth factor) receptor (EGFR) onto intraluminal vesicles (ILVs) of multivesicular...
Articles
Biochem Soc Trans (2016) 44 (1): 260–266.
Published: 09 February 2016
..., regulatory interactions and role in disease of the type III PI4Ks. 1 To whom correspondence should be addressed (email jeburke@uvic.ca ). 30 11 2015 © 2016 Authors; published by Portland Press Limited 2016 lipid signalling malaria membrane recruitment membrane trafficking...
Articles
Biochem Soc Trans (2015) 43 (1): 92–96.
Published: 26 January 2015
... correspondence should be addressed (email sfnovick@ucsd.edu ) . 17 9 2014 © The Authors Journal compilation © 2015 Biochemical Society 2015 COPII vesicle macroautophagy membrane trafficking TRAPP complex Ypt1 Macroautophagy is a catabolic process designed to rid the cell...
Articles
Biochem Soc Trans (2012) 40 (6): 1348–1352.
Published: 21 November 2012
.... Brucella endoplasmic reticulum intracellular bacterium membrane trafficking Rab2 Rab GTPase Brucellosis is the most common bacterial zoonotic disease worldwide, with over half a million infected people reported annually [ 1 ]. It remains endemic in many parts of the world, including...
Articles
Biochem Soc Trans (2010) 38 (6): 1397–1412.
Published: 24 November 2010
...) membrane trafficking viral budding The ESCRT machinery was originally identified as the Class-E subset of VPS (vacuolar protein sorting) genes, required for the correct sorting of soluble hydrolases from the yeast Golgi to the vacuole. These Class-E vps mutants were characterized...
Articles
Biochem Soc Trans (2009) 37 (5): 1032–1036.
Published: 21 September 2009
... (FIP3 and FIP4). Recent studies have identified the FIPs as key players in the regulation of multiple distinct membrane trafficking events. In this mini-review, we summarize the Rab11-FIP field and discuss, at molecular and cellular levels, the recent findings on FIP function. 1 To whom...
Articles
Biochem Soc Trans (2006) 34 (5): 927–930.
Published: 25 October 2006
... on the identification and characterization of functions of interacting partners. glutamate receptor kainate receptor-interacting protein membrane trafficking splice variant Kainate receptors are ionotropic glutamate receptors composed of various combinations of five subunits GluR5, GluR6, GluR7, KA1 and KA2...
Articles
Biochem Soc Trans (2006) 34 (3): 335–339.
Published: 22 May 2006
... transduction and membrane trafficking. Both the overall cholesterol content of a cell, as well as its distribution in specific organellar membranes are stringently regulated. Several diseases, many of which are incurable at present, have been characterized as results of impaired cholesterol transport...
Articles
Biochem Soc Trans (2006) 34 (3): 389–391.
Published: 22 May 2006
... endoplasmic reticulum junction lipid metabolism membrane trafficking Osh4p oxysterol-binding protein (OSBP) oxysterol-binding-protein-related protein (ORP) References 1 Lehto M. Olkkonen V.M. Biochim. Biophys. Acta 2003 1631 1 11 2 Loewen C.J.R. Roy A. Levine...
Articles
Biochem Soc Trans (2005) 33 (6): 1279–1281.
Published: 26 October 2005
...V. Kanamarlapudi The ARF (ADP-ribosylation factor) family of small GTPases regulate intracellular membrane trafficking by cycling between an inactive GDP- and an active GTP-bound form. Among the six known mammalian ARFs (ARF1–ARF6), ARF6 is the least conserved and plays critical roles in membrane...