...Kai Zhang; Victoria Chan; Roberto J. Botelho; Costin N. Antonescu Cardiolipin and phosphatidylinositol along with the latter's phosphorylated derivative phosphoinositides, control a wide range of cellular functions from signal transduction, membrane traffic, mitochondrial function, cytoskeletal...

... 29 Fukuda , M. ( 2008 ) Membrane traffic in the secretory pathway . Cell. Mol. Life Sci. 65 , 2801 – 2813 10.1007/s00018-008-8351-4 30 Loftus , S.K. , Larson , D.M. , Baxter , L.L. , Antonellis , A. , Chen , Y. , Wu , X. et al. ( 2002 ) Mutation...

....2005.11.015 16399085 14 Albertson R. Riggs B. Sullivan W. Membrane traffic: a driving force in cytokinesis Trends Cell Biol. 2005 15 92 101 10.1016/j.tcb.2004.12.008 15695096 15 Montagnac G. Echard A. Chavrier P. Endocytic traffic in animal cell cytokinesis...

... discussed the challenges that lie ahead with respect to its further characterization. The cytoplasm of eukaryotic cells consists of a wide variety of membrane-bound organelles each carrying out specific functions. Membrane traffic pathways between these organelles play key roles in transporting protein...

...Vasanth R. Singan; Kenan Handzic; Jeremy C. Simpson Membrane traffic pathways play an essential role in cells, providing a mechanism for organelles of the endomembrane system to communicate and exchange material between each other. A significant number of infections and diseases are associated...

... and freeing the SNARE motif to participate in SNARE complexes. However, whether these regulatory mechanisms are conserved throughout the Sx/SM protein families remains contentious as it is not clear whether the closed conformation represents a universal feature of Sxs. closed conformation membrane traffic...

... furrow during cytokinesis. 1 To whom correspondence should be addressed (email rytis.prekeris@uchsc.edu ). 15 2 2008 © The Authors Journal compilation © 2008 Biochemical Society 2008 cytokinesis exocyst FIP3 kinesin I membrane traffic recycling endosome Regulation...

...Arnaud Echard Growing evidence indicates that membrane traffic plays a crucial role during the late post-furrowing steps of cytokinesis in animal cells. Indeed, both endocytosis and exocytosis contribute to stabilizing the intercellular bridge that connects the daughter cells and to the final...

...J.G. Donaldson Arf (ADP-ribosylation factor) GTP-binding proteins function in cells to regulate membrane traffic and structure. Arfs accomplish this task through modification of membrane lipids and the recruitment of proteins, including coat proteins and actin, to membrane surfaces. Arf1 and Arf6...

... that has been instrumental in deciphering the molecular principles of membrane traffic at the Golgi. BFA targets a low-affinity Arf–Sec7 intermediate of the exchange reaction. It binds at the Arf-GDP/Sec7 interface, thus freezing the complex in an abortive conformation that cannot proceed to nucleotide...

...) proteins. At least six Arf family members were found in very early eukaryotes, including orthologues of Arf, Sar, Arl2, Arl3, Arl6 and Arl8. While roles for Arfs in membrane traffic are well known, those for most of the Arls remain unknown. Depletion in cells of the most closely related human Arf proteins...

... spatial coordinates during cleavage. In this review, we discuss recent work within the area of membrane traffic and cytokinesis. Figure 1 Rab11 is required for cytokinesis HeLa cells were infected with an adenovirus expressing a dominant negative mutant of Rab11 [Rab11-S25N (Ser 25 →Asn)]. Note...

... © 2005 The Biochemical Society 2005 GTPase guanine nucleotide dissociation inhibitor (GDI) membrane traffic prenylation Rab Rab escort protein (REP) Rab GTPases are initially synthesized as soluble proteins in the cytosol, which are post-translationally modified by prenylation...

... moving along microtubule tracks, whereas short-range transport involves the myosins moving along the actin filament network [ 1 ]. 21 6 2004 © 2004 The Biochemical Society 2004 actin endocytosis membrane traffic myosin optical tweezer 1 These authors have...