..., alternating between an orientation that lies across the membrane surface and an upright orientation that associates with the regulatory site of SERCA. circular dichroism (CD) fluorescence spectroscopy membrane binding NMR phospholamban Heart muscle relaxation is triggered by the rapid...

... to investigate the aggregation and membrane-binding properties of a synthetic peptide corresponding to this region. Results indicate that this region associates with phospholipid bilayers but also forms amyloid-like fibrils in the absence of lipid membranes. aggregation electron microscopy membrane binding...