... in their function: modulating their composition, size, density, and the network-like architecture in relation to the metabolic demands of the cell. Here, we review the recent research on the post-transcriptional regulation of mitochondrial composition focusing on mRNA localization, mRNA translation, protein import...

... be associated with translational repression or activation. Furthermore, mRNA P-bodies (processing bodies) harbour much of the mRNA decay machinery and stress granules are thought to play a role in mRNA storage. In the present review, we explore the process of mRNA localization in the yeast Saccharomyces...

... The Authors Journal compilation © 2011 Biochemical Society 2011 cytoplasmic dynein Drosophila localization element microtubule mRNA localization Asymmetric distribution of protein molecules, and thus the establishment of specific functional domains within cells, is a general phenomenon...

... motors during the localization process. Important outstanding questions will also be highlighted. 1 email sbullock@mrc-lmb.cam.ac.uk 22 3 2011 © The Authors Journal compilation © 2011 Biochemical Society 2011 cytoskeletal motor motility mRNA localization mRNA–protein...

... that are solely involved in glucose fermentation. 1 To whom correspondence should be addressed (email mark.p.ashe@manchester.ac.uk ). 26 2 2010 © The Authors Journal compilation © 2010 Biochemical Society 2010 EGP-body glucose derepression mRNA localization processing body (P...

... microtubule-dependent transport mRNA localization Rab6 vesicle In the following sections, we discuss the characterized roles of BicD in dynein-mediated transport of cellular cargoes. BicD is essential for correct specification of the Drosophila oocyte. This is likely to be linked...

..., such as the Drosophila embryo, where the spatial and temporal localization of bicoid and gurken mRNAs, among others, is required to establish morphogen gradients. More recent studies have suggested that mRNA localization also occurs with transcripts coding for membrane-based or secreted proteins, and that localization...

...I. Mickleburgh; B. Burtle; D. Nury; H. Chabanon; Z. Chrzanowska-Lightowlers; J.E. Hesketh mRNA localization provides a mechanism for localized protein synthesis. mRNAs encoding certain proteins, including c-MYC, c-FOS, MT-1 (Metallothionein-1) and vimentin, are localized around the nuclei...