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Keywords: lncRNA
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Articles
Biochem Soc Trans (2022) 50 (2): 951–963.
Published: 06 April 2022
...Yun Ma; Siqi He; Tianhe Gu; Yixuan Liu; Shuya He; Zhisheng Jiang Long non-coding RNAs (lncRNAs) are a class of non-coding RNA with a length greater than 200 nt. It has a mRNA-like structure, formed by splicing after transcription, and contains a polyA tail and a promoter, of whom promoter plays...
Articles
Biochem Soc Trans (2021) 49 (6): 2549–2560.
Published: 09 December 2021
...Ana Cláudia Raposo; Miguel Casanova; Anne-Valerie Gendrel; Simão Teixeira da Rocha X-inactive-specific transcript ( Xist ) is a long non-coding RNA (lncRNA) essential for X-chromosome inactivation (XCI) in female placental mammals. Thirty years after its discovery, it is still puzzling how...
Articles
Biochem Soc Trans (2020) 48 (6): 2467–2481.
Published: 27 November 2020
... of the Biochemical Society 2020 chromatin lncRNA piRNA RNA matchmaking The term ‘RNA matchmaking' was initially used to describe RNA base-pairing activity (annealing) that is promoted by RNA binding proteins [ 1 , 2 ]. Early use of the term mainly described the activity of heterogeneous nuclear...
Articles
Biochem Soc Trans (2017) 45 (5): 1117–1124.
Published: 22 September 2017
... in order to establish totipotency in blastomeres of an early embryo. This remodeling involves replacement of maternal RNAs with zygotic RNAs through maternal RNA degradation and zygotic genome activation. This review is focused on expression and function of long noncoding RNAs (lncRNAs) and small RNAs...
Articles
Biochem Soc Trans (2017) 45 (4): 953–962.
Published: 07 July 2017
...Loretta Magagula; Maria Gagliardi; Jerolen Naidoo; Musa Mhlanga Termed ‘master gene regulators’ long ncRNAs (lncRNAs) have emerged as the true vanguard of the ‘noncoding revolution’. Functioning at a molecular level, in most if not all cellular processes, lncRNAs exert their effects systemically...