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Keywords: lipoprotein
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Biochem Soc Trans (2011) 39 (4): 984–988.
Published: 20 July 2011
.... Although PLTP was studied initially for its involvement in the metabolism of HDL (high-density lipoproteins) and reverse cholesterol transport (i.e. the metabolic pathway through which cholesterol excess can be transported from peripheral tissues back to the liver for excretion in the bile), it displays...
Biochem Soc Trans (2008) 36 (5): 1037–1044.
Published: 19 September 2008
... Society 2008 high-resolution mass spectrometry 4-hydroxynonenal (4HNE) lipoprotein oxidative stress post-translational modification protein oxidation PTMs (post-translational modifications) of proteins occur extensively throughout their lifetime in a cell. For certain proteins, rather...
Biochem Soc Trans (2008) 36 (3): 348–352.
Published: 21 May 2008
... 2008 © The Authors Journal compilation © 2008 Biochemical Society 2008 apoptosis diabetes mellitus lipoprotein lipotoxicity non-esterified fatty acid pancreatic β-cell In parallel with the increase in life expectancy of the last two centuries, lifestyles have changed...
Biochem Soc Trans (2006) 34 (6): 1370–1375.
Published: 25 October 2006
.... Increased endothelial cell death is considered to be an initial step of atherogenesis. Thus activation of PP2C by physiological unbound (‘free’) unsaturated fatty acids (liberated from lipoproteins) could represent a crucial mechanism in the development of atherosclerosis. 1 To whom correspondence...
Biochem Soc Trans (2006) 34 (3): 399–403.
Published: 22 May 2006
...J.E. Vance; B. Karten; H. Hayashi Compared with other organs, the brain is highly enriched in cholesterol. Essentially all cholesterol in the brain is synthesized within the brain; the blood–brain barrier prevents the import of plasma lipoproteins into the brain. Consequently, the brain operates...
Biochem Soc Trans (2004) 32 (5): 721–723.
Published: 26 October 2004
...N. Beglova; H. Jeon; C. Fisher; S.C. Blacklow The LDLR (low-density lipoprotein receptor) is a modular protein built from several distinct structural units: LA (LDLR type-A), epidermal growth factor-like and β-propeller modules. The low pH X-ray structure of the LDLR revealed long-range...
Biochem Soc Trans (2004) 32 (1): 147–150.
Published: 01 February 2004
...B. Engelmann Cellular membranes and plasma lipoproteins are less efficiently protected against oxidative stress than the various aqueous compartments of mammalian organisms. Here, previous results on the role of plasmalogens in lipid oxidation are evaluated on the basis of criteria required...
Biochem Soc Trans (2003) 31 (5): 1062–1065.
Published: 01 October 2003
...I.S. Young; C. McFarlane; J. McEneny Lipoprotein oxidation is thought to play a pivotal role in the evolution of atherosclerosis. Low-density lipoprotein (LDL) is the main source of oxidized lipid in the arterial wall. Oxidation of LDL alters its properties in a number of ways, making it more...
Biochem Soc Trans (2000) 28 (2): 113–120.
Published: 01 February 2000
.... In the case of lipids, metabolism of non-esterified fatty acids has been extensively investigated in the perfused rat heart, but fatty acids may also be derived from circulating triacylglycerols (TAG) in lipoproteins [chylomicrons, very-low-density-lipoprotein (VLDL)]. TAG requires initial hydrolysis...