...-bourgogne.fr ). 28 3 2011 © The Authors Journal compilation © 2011 Biochemical Society 2011 endotoxic shock inflammation lipopolysaccharide (LPS) lipoprotein phospholipid-transfer protein (PLTP) transgenic mouse model Lipoproteins are macromolecular complexes that transport...

... in Gram-negative bacteria-induced respiratory infection. 1 email peterdi@pitt.edu 5 4 2011 © The Authors Journal compilation © 2011 Biochemical Society 2011 antimicrobial peptide bacterium lipopolysaccharide (LPS) mucous cell serous cell short palate lung and nasal...

... C20orf70 endotoxin lipid binding lipopolysaccharide (LPS) parotid secretory protein (PSP) PSP (parotid secretory protein)/SPLUNC2 (short palate, lung and nasal epithelium clone 2) (C20orf70) is the predominant member of the PLUNC (palate, lung and nasal epithelium clone) family in saliva. PSP...

... 3 2010 © The Authors Journal compilation © 2010 Biochemical Society 2010 carbohydrate binding lipopolysaccharide (LPS) phage infection cycle Salmonella phage P22 tailspike Figure 1 Structure of P22TSP and its octasaccharide-binding domain ( A ) Structure of phage P22...

... proteins to the intracellular domain of TLR4, initiating the intracellular signal cascade that culminates in translocation of transcription factors to the nucleus and the biosynthesis of cytokines. CD14 inflammation lipid A lipopolysaccharide (LPS) myeloid differentiation protein 2 (MD-2...

... To whom correspondence should be addressed (email Barbara.Mulloy@nibsc.hpa.org.uk ). 4 8 2010 © The Authors Journal compilation © 2010 Biochemical Society 2010 glycobiology glycosaminoglycan (GAG) heparan sulfate lipopolysaccharide (LPS) O-linked β- N -acetylglucosamine (O-GlcNAc...

... The Authors Journal compilation © 2007 Biochemical Society 2007 ectodomain homology modelling leucine-rich repeat lipopolysaccharide (LPS) Molecular Dynamics myeloid differentiation factor 88 (MyD88) Toll-like receptor (TLR) In mammals, the sensing of different microbial pathogens...

... The Authors Journal compilation © 2007 Biochemical Society 2007 adenocarcinoma chemokine colitis interleukin-10 (IL-10) lipopolysaccharide (LPS) Toll-like receptor 4 (TLR4) Chronic intestinal inflammatory conditions such as ulcerative colitis are associated with an increased risk...

... ischaemic injury lipopolysaccharide (LPS) neuroprotection tolerance Toll-like receptor (TLR) tumour necrosis factor (TNF) Ischaemic tolerance in the brain (in which brief ischaemia increases resistance to subsequent injurious ischaemia) is a powerful adaptive defence that involves an endogenous...

... endotoxin tolerance lipopolysaccharide (LPS) M1/M2 macrophages Src homology 2-containing inositol 5′-phosphatase (SHIP) Figure 1 Two models for SHIP1 recruitment to the plasma membrane Left panel: IL-3 stimulates the Jak2-mediated tyrosine phosphorylation of the β IL-3 subunit of the IL...

... B cell innate immune response lipopolysaccharide (LPS) phosphoinositide 3-kinase RP105 Toll-like receptor Intracellular signalling is the basis for cellular responses and signals can be transduced through a variety of pathways. A key player in multiple routes of signal transduction...

...) inflammation NF-E2-related factor 2 (Nrf2) lipopolysaccharide (LPS) cytokine AP-1 activator protein 1 ARE antioxidant response element HO-1 haem oxygenase-1 LPS lipopolysaccharide NF-κB nuclear factor-κB Nrf2 NF-E2-related factor 2 PKC protein kinase C...

... the Cy3 filter sets. Hsp70 Hsp90 innate recognition lipopolysaccharide (LPS) LPS-activation cluster Toll-like receptor 4 (TLR4) Hsps (heat-shock proteins) are a family of highly conserved proteins found in cells. Hsps are constitutively expressed intracellularly, and act as molecular...