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Keywords: lipidation
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Biochem Soc Trans (2017) 45 (1): 275–285.
Published: 15 February 2017
.... Protein S-acylation or S-palmitoylation involves the posttranslational addition of fatty acyl chains, typically a palmitate (C16:0), to cysteine residues of proteins via thioester linkages ( Figure 1A ). In contrast with other forms of protein lipidation, S-palmitoylation is uniquely reversible due...
Biochem Soc Trans (2015) 43 (2): 262–267.
Published: 07 April 2015
... and sequesters Hh spreading by endocytotic internalization and the activation of HhNp degradation [ 15 , 16 ]. Although Ptc contains the sterol-sensing domain (SSD; similar to proteins involved in cholesterol biogenesis, homoeostasis or lipid storage) [ 17 ], ShhNp and ShhN have comparable binding affinities...