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Keywords: lipid raft
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Articles
Biochem Soc Trans (2016) 44 (1): 228–233.
Published: 09 February 2016
... far lacking. 1 email ghammond@pitt.edu . 2 11 2015 © 2016 Authors; published by Portland Press Limited 2016 lipid raft microdomain nanoscopy phosphoinositide The three proposed models for how PtdIns(4,5) P 2 multi-tasks share a common feature: they all lead...
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Biochem Soc Trans (2011) 39 (3): 819–822.
Published: 20 May 2011
..., with the greatest inhibition of PMCA4. Besides, cholesterol blocked the inhibitory effect of Aβ, which is consistent with the lack of any Aβ effect on PMCA4 found in cholesterol-enriched lipid rafts isolated from pig brain. These observations suggest that PMCAs are a functional component of the machinery that leads...
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Biochem Soc Trans (2009) 37 (5): 1056–1060.
Published: 21 September 2009
..., Australia. 29 4 2009 © The Authors Journal compilation © 2009 Biochemical Society 2009 eukaryotic cell fluorescence microscopy lipid raft membrane lipid order multimolecular assembly supramolecular complex The outer walls of buildings protect the interiors from the outside...
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Biochem Soc Trans (2008) 36 (6): 1472–1477.
Published: 19 November 2008
... for organizing plasma membrane domains, such as lipid rafts, or for targeted delivery of glycoproteins to the apical or basolateral surface. Galectin–glycan lattice formation is also involved in regulating the signalling threshold of some cell-surface glycoproteins, including T-cell receptors and growth factor...
Articles
Biochem Soc Trans (2008) 36 (6): 1272–1276.
Published: 19 November 2008
... cells expressing PrP c to Cu 2+ results in the rapid endocytosis of the protein. First, PrP c translocates laterally out of detergent-resistant lipid rafts into detergent-soluble regions of the plasma membrane, then it is internalized through clathrin-coated pits. The extreme N-terminal region of PrP c...
Articles
Biochem Soc Trans (2005) 33 (6): 1313–1315.
Published: 26 October 2005
... activates a pool of SFK in lipid rafts/caveolae for c- myc induction and DNA synthesis and another pool outside lipid rafts/caveolae for actin assembly. Activation of this second pool is through cross-talk signalling: PDGF recruits S1K (sphingosine 1-kinase) to the membrane through a phospholipase Cγ (PLCγ...
Articles
Biochem Soc Trans (2005) 33 (5): 1219–1223.
Published: 26 October 2005
... albicans drug resistance ergosterol lipid raft morphogenesis sphingolipid The existence of discrete membrane microdomains, known as lipid rafts within a lipid bilayer, predominantly composed of sphingolipid and sterol, are well documented in several systems [ 1 – 5 ]. Interestingly...
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Biochem Soc Trans (2005) 33 (6): 1319–1322.
Published: 26 October 2005
... involving ACs in lipid rafts, held there by protein–protein interactions with other raft residents, along with CCE channel components, NHE1, gravin, PKA and PDE4D, and in which cAMP kinetics differ dramatically from those that reach the cytosol, and which therefore may evoke distinct signalling consequences...
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Biochem Soc Trans (2004) 32 (5): 712–714.
Published: 26 October 2004
... in its active or cholesterol-inactivated forms specifically binds to and aggregates lipid rafts, thus co-clustering different rafts-associated proteins. We then evaluated whether rafts aggregation by LLO translates into signalling. To that end, lysates of J774 cells stimulated with HA–LLO and CL...
Articles
Biochem Soc Trans (2004) 32 (3): 461–464.
Published: 01 June 2004
.... Edinburgh, 19–20 November 2003 25 November 2003 © 2004 Biochemical Society 2004 1 To whom correspondence should be addressed (email J.M.Lord@bham.ac.uk ). apoptosis Bcl-2 caspase 8 death receptor lipid raft inflammation neutrophil Abbreviations used: DISC, death...
Articles
Biochem Soc Trans (2004) 32 (1): 65–69.
Published: 01 February 2004
...C.J. Fielding; P.E. Fielding The plasma membrane of mammalian cells consists of microdomains differing in lipid and protein composition. Two distinct classes of cholesterol/sphingolipid microdomain (caveolae and lipid rafts) are assembly points for transmembrane signalling complexes. Recent...