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Keywords: lipid raft
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Articles
Biochem Soc Trans (2016) 44 (1): 228–233.
Published: 09 February 2016
...@pitt.edu . 2 11 2015 © 2016 Authors; published by Portland Press Limited 2016 lipid raft microdomain nanoscopy phosphoinositide The plasma membrane (PM) of any eukaryotic cell is a frenetic hub of activity. It mediates a ceaseless exchange of minerals, nutrients and waste...
Articles
Biochem Soc Trans (2011) 39 (3): 819–822.
Published: 20 May 2011
..., with the greatest inhibition of PMCA4. Besides, cholesterol blocked the inhibitory effect of Aβ, which is consistent with the lack of any Aβ effect on PMCA4 found in cholesterol-enriched lipid rafts isolated from pig brain. These observations suggest that PMCAs are a functional component of the machinery that leads...
Articles
Biochem Soc Trans (2009) 37 (5): 1056–1060.
Published: 21 September 2009
... © The Authors Journal compilation © 2009 Biochemical Society 2009 eukaryotic cell fluorescence microscopy lipid raft membrane lipid order multimolecular assembly supramolecular complex The outer walls of buildings protect the interiors from the outside environment. Windows...
Articles
Biochem Soc Trans (2008) 36 (6): 1472–1477.
Published: 19 November 2008
... for organizing plasma membrane domains, such as lipid rafts, or for targeted delivery of glycoproteins to the apical or basolateral surface. Galectin–glycan lattice formation is also involved in regulating the signalling threshold of some cell-surface glycoproteins, including T-cell receptors and growth factor...
Articles
Biochem Soc Trans (2008) 36 (6): 1272–1276.
Published: 19 November 2008
... cells expressing PrP c to Cu 2+ results in the rapid endocytosis of the protein. First, PrP c translocates laterally out of detergent-resistant lipid rafts into detergent-soluble regions of the plasma membrane, then it is internalized through clathrin-coated pits. The extreme N-terminal region of PrP c...
Articles
Biochem Soc Trans (2005) 33 (6): 1313–1315.
Published: 26 October 2005
... christine.benistant@crbm.cnrs.fr ). 6 7 2005 © 2005 The Biochemical Society 2005 actin assembly cell compartmentalization DNA synthesis growth factor lipid raft Src family tyrosine kinase In addition to mitogenesis, PDGF also induces F-actin circular dorsal ruffles ( Figure 2...
Articles
Biochem Soc Trans (2005) 33 (5): 1131–1134.
Published: 26 October 2005
... signalling components are organized together in membrane microdomains, in particular lipid rafts, enriched in cholesterol and sphingolipids, and caveolae, a subset of lipid rafts that also possess the protein caveolin, whose scaffolding domain may serve as an anchor for signalling components. Caveolae were...
Articles
Biochem Soc Trans (2005) 33 (6): 1319–1322.
Published: 26 October 2005
... involving ACs in lipid rafts, held there by protein–protein interactions with other raft residents, along with CCE channel components, NHE1, gravin, PKA and PDE4D, and in which cAMP kinetics differ dramatically from those that reach the cytosol, and which therefore may evoke distinct signalling consequences...
Articles
Biochem Soc Trans (2005) 33 (5): 1219–1223.
Published: 26 October 2005
... A. Kolter R. Morschhauser J. Gene 2004 341 119 127 Candida albicans drug resistance ergosterol lipid raft morphogenesis sphingolipid The existence of discrete membrane microdomains, known as lipid rafts within a lipid bilayer, predominantly composed of sphingolipid...
Articles
Biochem Soc Trans (2005) 33 (2): 335–338.
Published: 01 April 2005
... for the α-cleavage of PrP C . The amyloidogenic cleavage of APP by the β- and γ-secretases appears to occur preferentially in cholesterol-rich lipid rafts, while the conversion of PrP C into the infectious form PrP Sc also appears to occur in these membrane domains. 1 email n.m.hooper@leeds.ac.uk...
Articles
Biochem Soc Trans (2004) 32 (5): 837–839.
Published: 26 October 2004
... of serine/threonine (but not tyrosine) phosphatases. Our results imply that destabilization of lipid rafts seemingly affects the association of Hsp90 with the respective serine/threonine phosphatases, thereby increasing the accessibility to PKB/Akt to deactivating phosphatases. We have found recently...
Articles
Biochem Soc Trans (2004) 32 (5): 712–714.
Published: 26 October 2004
.... 2001 98 9642 9647 8 7 2004 © 2004 The Biochemical Society 2004 cholesterol glycosylphosphatidylinositol anchor lipid raft Listeria monocytogenes listeriolysin O oligomerization Fifteen years after the formulation of the rafts hypothesis [ 1 – 3 ], considerable...
Articles
Biochem Soc Trans (2004) 32 (3): 461–464.
Published: 01 June 2004
... of neutrophil numbers in the circulation, the efficient removal of invading pathogens and resolution of the inflammatory response. Key words: apoptosis, Bcl-2, caspase 8, death receptor, lipid raft, inflammation, neutrophil. Abbreviations used: DISC, death-inducing signalling complex; DR, death receptor; FADD...
Articles
Biochem Soc Trans (2004) 32 (1): 65–69.
Published: 01 February 2004
...C.J. Fielding; P.E. Fielding The plasma membrane of mammalian cells consists of microdomains differing in lipid and protein composition. Two distinct classes of cholesterol/sphingolipid microdomain (caveolae and lipid rafts) are assembly points for transmembrane signalling complexes. Recent...