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Keywords: leukaemic stem cell (LSC)
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Biochem Soc Trans (2016) 44 (5): 1455–1463.
Published: 19 October 2016
... (HSC) giving rise to a leukaemic stem cell (LSC) within the bone marrow (BM) ‘niche’. CML is characterised by the presence of the oncogenic tyrosine kinase fusion protein breakpoint cluster region-abelson murine leukaemia viral oncogene homolog 1 (BCR-ABL), which is responsible for driving the disease...
Biochem Soc Trans (2005) 33 (6): 1531–1533.
Published: 26 October 2005
... correspondence should be addressed (email dominique.bonnet@cancer.org.uk ). 17 6 2005 © 2005 The Biochemical Society 2005 cancer stem cell (CSC) haematopoietic stem cell (HSC) leukaemic stem cell (LSC) self-renewal tumour xenotransplantation model The hallmark properties of HSCs...