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Keywords: leucine rich repeat kinase
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Biochem Soc Trans (2022) 50 (1): 621–632.
Published: 28 February 2022
...Federica Albanese; Chiara Domenicale; Mattia Volta; Michele Morari Mutations in the leucine-rich repeat kinase 2 ( LRRK2 ) gene are associated with familial and sporadic forms of Parkinson's disease (PD), for which the LRRK2 locus itself represents a risk factor. Idiopathic and LRRK2-related PD...
Biochem Soc Trans (2020) 48 (5): 2185–2194.
Published: 20 October 2020
...Ahmed Soliman; Fatma Nihan Cankara; Arjan Kortholt Parkinson's disease (PD) is the second most common neurodegenerative disease. In recent years, it has been shown that leucine-rich repeat kinase 2 (LRRK2) has a crucial function in both familial and sporadic forms of PD. LRRK2 pathogenic mutations...