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Keywords: lectin
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Articles
Biochem Soc Trans (2019) 47 (1): 89–100.
Published: 17 December 2018
... antibodies or lectins and/or characterized with analytical techniques such as chromatography and mass spectrometry. The glycan structures on glycoproteins and glycolipids expressed in neural stem cells play key roles in neural development, biological processes and CNS maintenance, such as cell adhesion...
Articles
Biochem Soc Trans (2018) 46 (2): 217–233.
Published: 22 February 2018
...Sofie Van Holle; Els J.M. Van Damme Lectins constitute an abundant group of proteins that are present throughout the plant kingdom. Only recently, genome-wide screenings have unraveled the multitude of different lectin sequences within one plant species. It appears that plants employ a plurality...
Articles
Biochem Soc Trans (2012) 40 (6): 1433–1437.
Published: 21 November 2012
... should be addressed (email Chris.Penfold@nottingham.ac.uk ). 24 9 2012 © 2012 The Authors Journal 2012 bacterial ecology bacteriocin colicin enterocin lectin microbial competition Presentations at the meeting were supported and enhanced by a large number of very high...
Articles
Biochem Soc Trans (2011) 39 (1): 399–405.
Published: 19 January 2011
.... They are brought about by altering the interplay between the glycan and (i) its carrier protein and (ii) specific receptors (lectins). Glycan attachment thus endows the protein with a molecular switch and new recognition sites. Co-ordinated regulation of glycan display and presentation of the cognate lectin, e.g...
Articles
Biochem Soc Trans (2010) 38 (5): 1333–1336.
Published: 24 September 2010
.... This glycomic information is highly relevant for clinicians and biomanufacturing industries as a new class of glycobiomarkers emerges. However, current methods of glycoanalysis are primarily research tools and are not suitable for point-of-care on-site detection and analysis, or sensor devices. Lectin-based...
Articles
Biochem Soc Trans (2008) 36 (6): 1453–1456.
Published: 19 November 2008
... and the ability of carbohydrate-binding proteins (lectins) to decipher this ‘glycocode’. Approx. 120 participants attended the 23rd International Lectin Meeting (Interlec-23) held at the Universities of Edinburgh (2 days) and Stirling (4 days) between 11 and 16 July 2008. These ‘Interlecs’ are truly international...
Articles
Biochem Soc Trans (2008) 36 (6): 1457–1460.
Published: 19 November 2008
...Nathan Sharon Lectins, a class of sugar-binding and cell-agglutinating proteins, are ubiquitous in Nature, being found in all kinds of organisms, from viruses to humans. This review describes how plant lectins were developed as widely used reagents for the study of glycoconjugates in solution...
Articles
Biochem Soc Trans (2008) 36 (6): 1467–1471.
Published: 19 November 2008
...Paul R. Crocker; Pierre Redelinghuys Siglecs (sialic acid-binding Ig-like lectins) are mainly expressed in the immune system. Sn (sialoadhesin) (siglec-1), CD22 (siglec-2) and siglec-15 are well conserved, whereas the CD33-related siglecs are undergoing rapid evolution, as reflected in large...
Articles
Biochem Soc Trans (2008) 36 (6): 1482–1486.
Published: 19 November 2008
... interactions between the epithelium and lectins of dietary, microbial or human origin. Different TF-binding lectins cause diverse effects on epithelial cells, reflecting subtle differences in binding specificities e.g. for sialylated TF; some of these interactions, such as with the TF-binding peanut lectin...
Articles
Biochem Soc Trans (2008) 36 (6): 1491–1496.
Published: 19 November 2008
... favourably with highly flexible peptides (third dimension of the sugar code). Sequence, shape and local aspects of glycan presentation (e.g. multivalency) are key factors to regulate the avidity of lectin binding. At the level of cells, distinct glycan determinants, a result of enzymatic synthesis...
Articles
Biochem Soc Trans (2008) 36 (5): 843–847.
Published: 19 September 2008
... analyses in Arabidopsis and rice revealed the presence of F-box proteins with a C-terminal lectin-related domain homologous with Nictaba, a jasmonate-inducible lectin from tobacco that was shown to interact with the core structure of high-mannose and complex N-glycans. Owing to the high similarity...
Articles
Biochem Soc Trans (2007) 35 (2): 340–342.
Published: 20 March 2007
... the lectin phytohaemagglutinin is included in the diet, a fully reversible dose-dependent growth of the small intestine occurs leading to an extensive accumulation of polyamines in the intestinal epithelia. This approach of reducing the availability of exogenous polyamines to a growing tumour...