.... 1 To whom correspondence should be addressed (email galila@bgu.ac.il ). 13 4 2009 © The Authors Journal compilation © 2009 Biochemical Society 2009 bipolar disorder glycogen synthase kinase 3β (GSK3β) inositol monophosphatase (IMPase) knockout mouse lithium sodium– myo...

... autoimmunity knockout mouse phosphoinositide 3-kinase (PI3K) regulatory T-cell (Treg) T-cell thymocyte Until recently, the best evidence for an important role of PI3K and its downstream effectors in T-cell function was derived from mouse models of gain of function [ 2 ]. Mice heterozygous...

... of Lipids, a meeting held at Keble College, Oxford, 7–11 September 2003 7 September 2003 © 2004 Biochemical Society 2004 apolipoprotein E (apoE) atherosclerosis inflammation knockout mouse serum chemokine Abbreviations used: apoE, apolipoprotein E; oxLDL, oxidized low...

... homeostasis. 1 e-mail rohit.kulkarni@joslin.harvard.edu 19 10 2001 © 2002 Biochemical Society 2002 IRS, insulin receptor substrate IGF, insulin-like growth factor βIRKO, β-cell insulin receptor knockout βIGFRKO, β-cell IGF-1 receptor knockout β-cell knockout mouse...

... of the insulin receptor causes a similar phenotype, these findings implicate IRS signalling pathways in the neuroendocrine regulation of reproduction and energy homeostasis. 1 e-mail d.withers@ic.ac.uk 7 3 2001 © 2001 Biochemical Society 2001 insulin knockout mouse metabolism...