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Keywords: knockout
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Biochem Soc Trans (2010) 38 (6): 1655–1659.
Published: 24 November 2010
... describe how we generated DT40 conditional-knockout cell lines for incenp1 and survivin1 to better understand the role of these CPC subunits in the control of Aurora B kinase activity. These lines enabled us to reassess current knowledge of survivin function and to show that INCENP acts as a rheostat...