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Keywords: kinetic modelling
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Articles
Biochem Soc Trans (2015) 43 (4): 586–592.
Published: 03 August 2015
... that the use of a kinetic model that describes with some degree of fidelity the underlying biology of the tissue is key to obtain meaningful parameters. At the same time, both tissue and plasma concentrations need to be measured accurately; this is occasionally impeded by limitations of the instrumentation...
Articles
Biochem Soc Trans (2010) 38 (5): 1275–1280.
Published: 24 September 2010
... G-protein-coupled receptor (GPCR) kinetic modelling Leber congenital amaurosis phototransduction rod systems biology The primary events in vertebrate vision are the biochemical steps in the phototransduction cascade in rods and cones, the retinal photoreceptor cells. This signal...
Articles
Biochem Soc Trans (2003) 31 (6): 1409–1412.
Published: 01 December 2003
... null mutant, lacking aldose reductase activity, is as sensitive as the control strain. Kinetic modelling and computer simulation of this type of experiment were also performed, and we concluded that the most important parameters for controlling the intracellular concentration of methylglyoxal...