... important constraint in kinetic modelling [ 14 ]. The steady state of metabolism (concentrations of internal metabolites are constant while at least one flux has non-zero value) is frequently requested in kinetic modelling and optimization looking for biotechnologically applicable strain designs: organisms...

... into the glyoxylate cycle. When ACN1 is not present, carbon in the form of acetate can leak out of peroxisomes and is reactivated to acetyl-CoA within the cytosol. Kinetic models incorporating estimates of carbon input and pathway dynamics from a variety of literature sources have proven useful in explaining how ACN1...