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Keywords: islet graft rejection
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Journal:
Biochemical Society Transactions
Biochem Soc Trans (2008) 36 (3): 334–339.
Published: 21 May 2008
...Danielle Melloul Apoptotic β-cell death appears to be central to the pathogenesis of Type 1 diabetes mellitus and in islet graft rejection. The β-cell destruction is partially mediated by cytokines, such as IL-1β (interleukin 1β), TNFα (tumour necrosis factor α) and IFN-γ (interferon γ). IL-1β...
