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Keywords: intracellular targeting
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Biochem Soc Trans (2007) 35 (4): 833–834.
Published: 20 July 2007
... (modular antigen translocation) molecules, aimed to enhance antigen presentation through intracellular targeting of the MHC II presentation pathway. MAT vaccines consist of a cloning cassette, which fuses Tat (transactivator of transcription) peptide to a truncated Ii (invariant chain), which is able...
Biochem Soc Trans (2004) 32 (2): 338–342.
Published: 01 April 2004
... domains that bind PtdIns(3,4,5) P3 and are essential for the efficient phosphorylation and hence activation of PKB. PKB and PDK1 each phosphorylate Key words: intracellular targeting, PtdIns(3,4,5)P3 , PTEN (phosphatase and tensin homologue deleted on chromosome 10), reactive oxygen species, TPIP (TPTE...