... Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . haemopoiesis intracellular signalling mechanistic target of rapamycin Mechanistic target of rapamycin (mTOR) is a serine/threonine protein kinase which was initially...

... dysfunction plays a role. cAMP cyclic nucleotide phosphodiesterases intracellular signalling mitochondria AKAP A-kinase anchoring protein ATP adenosine triphosphate BAD Bcl2 associated death promoter Br-cAMP brome cyclic AMP cAMP 3′-5′-cyclic adenosine monophosphate...

... Biochemical Society 2008 intracellular signalling interleukin-1-receptor-associated kinase (IRAK) nuclear factor κB (NF-κB) Toll-like receptor tumour-necrosis-factor-receptor-associated factor-6 (TRAF-6) vaccinia virus Interestingly, expression of IRAK-2, but not IRAK-1, led to TRAF-6...

...J.A. Johnston; J.F. Burrows Ubiquitination is now accepted as an important process for regulating intracellular signalling and the realization that many known signalling molecules exhibit E3 ligase activity has led to great strides in our understanding of how these pathways are regulated. However...

...S.C. Tovey; S.G. Dedos; C.W. Taylor PTH (parathyroid hormone), acting via type 1 PTH receptors, is a major regulator of plasma [Ca 2+ ]. The G-protein, G s , is an essential component of the sequence linking PTH to plasma Ca 2+ regulation, but the relative importance of intracellular signals...