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Keywords: intestinal stem cells
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Biochem Soc Trans (2021) 49 (5): 2163–2176.
Published: 19 October 2021
... and are derived from adult intestinal stem cells (ISCs). Actively cycling ISCs divide by a neutral drift mechanism yielding either ISCs or transit-amplifying epithelial cells, the latter of which differentiate to become either absorptive lineages or to produce secretory factors that contribute further...