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Keywords: interleukin
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Biochem Soc Trans (2018) 46 (5): 1345–1353.
Published: 09 October 2018
...Ian C. Scott; D. Gareth Rees; E. Suzanne Cohen Interleukin (IL)-1 family cytokines are important initiators of innate immunity and host defence; however, their uncontrolled activities can cause tissue-damaging inflammation. Consequently, IL-1 family cytokines have sophisticated regulatory...
Biochem Soc Trans (2009) 37 (4): 830–837.
Published: 22 July 2009
... with progressive fibrosis in the lung. Finally, the predominant inflammatory cell in ARDS (acute respiratory distress syndrome) is the neutrophil, with levels of the neutrophil chemoattractant IL (interleukin) -8 related to outcomes suggesting that an increase in the number of neutrophils leads to more tissue...
Includes: Multimedia, Supplementary data
Biochem Soc Trans (2007) 35 (5): 1163–1165.
Published: 25 October 2007
... blood–brain barrier CRP C-reactive protein IL interleukin LPS lipopolysaccharide References 1 Hankey G.J. Stroke 2006 37 2181 2188 2 Muir K.W. Tyrrell P. Sattar N. Warburton E. Curr. Opin. Neurol. 2007 20 334 342 3 Warlow C...
Biochem Soc Trans (2007) 35 (5): 1295–1297.
Published: 25 October 2007
... muscles express several cytokines, which belong to distinct cytokine classes. IL-6 (interleukin-6) is a pleiotropic cytokine produced by virtually all multinucleated cells including skeletal myocytes where it is produced in response to contraction. IL-6 is subsequently released into the circulation, where...
Biochem Soc Trans (2004) 32 (3): 489–492.
Published: 01 June 2004
... Focused Meeting held at New Edinburgh Royal Infirmary, Little France, Nr. Edinburgh, 19–20 November 2003 25 November 2003 © 2004 Biochemical Society 2004 apoptosis Bcl-2 interleukin Mcl-1 neutrophil Abbreviations used: Bcl-2, B-cell lymphocytic-leukaemia proto-oncogene...
Biochem Soc Trans (2003) 31 (3): 637–642.
Published: 01 June 2003
... an extracellular leucine-rich repeat domain and cytoplasmic domain homologous with that of the interleukin 1 receptor (IL-1R) family. Upon stimulation, TLR recruits the IL-1R-associated kinase (IRAK) via the adapter MyD88, ultimately leading to the activation of nuclear factor-κB. Cytokine production in response...
Biochem Soc Trans (2003) 31 (3): 664–668.
Published: 01 June 2003
... RNA-dependent protein kinase)-independent, but TIRAP (Toll/interleukin-1 receptor domain-containing adapter protein)/Mal (MyD88-adapter-like)-dependent. In the present paper, we outline the recent controversy over the role of TIRAP/Mal in TLR2 and TLR4 signalling in the context of the current...