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Keywords: inter-α-inhibitor
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Biochem Soc Trans (2007) 35 (4): 672–676.
Published: 20 July 2007
...C.M. Milner; W. Tongsoongnoen; M.S. Rugg; A.J. Day The inflammation-associated protein TSG-6 (the product of tumour necrosis factor-stimulated gene-6) can form covalent complexes with the heavy chains (HC1 and HC2) of IαI (inter-α-inhibitor); namely, TSG-6·HC1 and TSG-6·HC2, which act...
Biochem Soc Trans (2006) 34 (3): 446–450.
Published: 22 May 2006
.... For example, through its association with HA, TSG-6 can mediate HA cross-linking via several different mechanisms, some of which promote leucocyte adhesion. Binding to heparin, however, enhances the ability of TSG-6 to potentiate the anti-plasmin activity of inter-α-inhibitor, which binds non-covalently...