... worldwide, and have a significant financial impact on society. Assembly and budding of new viral particles are a complex and multi-step process involving several host and viral factors. Influenza viruses use lipid raft domains in the apical plasma membrane of polarized epithelial cells as sites of budding...

... not play an essential role for the life cycle of influenza viruses, it is hard to conceive why they have not been exchanged by similar amino acids during evolution of influenza viruses. Indeed, it was impossible to generate influenza virus mutants with two or three HA palmitoylation sites removed, implying...

... 3 Zimmerberg J. Vogel S.S. Chernomordik L.V. Mechanisms of membrane fusion Annu. Rev. Biophys. Biomol. Struct. 1993 22 433 466 4 White J. Helenius A. Gething M.J. Hemagglutinin of influenza virus expressed from a cloned gene promotes membrane-fusion Nature...