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Keywords: inflammatory disease
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Biochem Soc Trans (2011) 39 (2): 669–673.
Published: 22 March 2011
... caspase 1 and to the production of mature IL-1β (interleukin 1β). The discovery that NLRP3 (NLR-related protein 3) can recognize host-derived particulate matter such as uric acid and cholesterol crystals has led to this inflammasome being implicated in a number of inflammatory diseases, including gout...