... imprinting. The paternal antisense transcript Air regulates the maternally expressed igf2 receptor gene ( igf2r ). Air only directly overlaps with igf2r , while it silences the expression of igf2r , Slc22a2 and Slc22a3 through an ill-defined epigenetic modification [ 10 ]. There are also examples...

..., is an important part of the mechanisms that govern X-chromosome inactivation; it is also essential for the maintenance of imprinted genes and, at least in some cases, is critical in determining the cell-type-specific expression patterns of genes. Study of these examples will be important in identifying...