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Keywords: immune response
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Articles
Biochem Soc Trans (2022) BST20220244.
Published: 16 September 2022
... in HIC patients. HLA-B57 can present a large range of highly conserved Gag-derived HIV peptides to CD8 + T cells and natural killer (NK) cells, both the focus of this review. So far there are limited differences in the immune response strength, magnitude, or receptor repertoire towards HIV epitopes...
Articles
Biochem Soc Trans (2022) 50 (2): 825–837.
Published: 28 March 2022
... with Portland Press and the Biochemical Society under a transformative agreement with CAUL. cancer immune response major histocompatibility complex The advent of immunotherapeutics has revolutionised treatment in cancer. These agents harness our immune system to promote anti-tumour responses...
Articles
Biochem Soc Trans (2021) 49 (2): 881–891.
Published: 16 April 2021
..., virulence and immune response mechanisms. Mammalian EVs play an increasingly recognised role to fight infection, yet may also be commandeered to disseminate pathogens and enhance infection. EVs released by bacterial pathogens may deliver toxins to host cells, signalling molecules and new DNA to other...
Articles
Biochem Soc Trans (2018) 46 (5): 1345–1353.
Published: 09 October 2018
... local immune responses by stimulating innate immune cells following exposure to environmental insults, pathogens, or sterile injury. Recent publications have provided new insights into how the range and duration of IL-33 activity is regulated by direct sensing of host-derived and exogenous proteolytic...
Articles
Biochem Soc Trans (2017) 45 (4): 905–911.
Published: 03 July 2017
...@inflammation-metabolism.dk ) 13 3 2017 29 5 2017 1 6 2017 © 2017 The Author(s); published by Portland Press Limited on behalf of the Biochemical Society 2017 biomarkers cytokines exercise oncology immune response physical training physiology Evasion of immune...
Articles
Biochem Soc Trans (2011) 39 (1): 360–364.
Published: 19 January 2011
...Karin Hoffmann-Sommergruber; Katharina Paschinger; Iain B.H. Wilson Both helminth infections and contact with allergens result in development of a Th2 type of immune response in the affected individual. In this context, the hygiene hypothesis suggests that reduced prevalence of parasitic infections...
Articles
Biochem Soc Trans (2008) 36 (5): 879–884.
Published: 19 September 2008
...-mediated de novo formation of different proteasome compositions as i20S (immunoproteasomes) or m20S (mixed-type proteasomes) essentially supports the rapid adjustment of the mammalian immune system to pathogens. This adjustment is of particular importance for the immune response to rapidly replicating...
Articles
Biochem Soc Trans (2008) 36 (2): 203–211.
Published: 20 March 2008
... that regulate leucocyte trafficking. 1 To whom correspondence should be addressed (email beat.imhof@medecine.unige.ch ). 28 11 2007 © The Authors Journal compilation © 2008 Biochemical Society 2008 adhesion immune response inflammation junctional adhesion molecule (JAM) leucocyte...
Articles
Biochem Soc Trans (2007) 35 (5): 1114–1118.
Published: 25 October 2007
... correspondence should be addressed (email rachel.david00@imperial.ac.uk ). 6 6 2007 © The Authors Journal compilation © 2007 Biochemical Society 2007 CD28 co-stimulatory molecule cytotoxic T-lymphocyte-associated protein-4 (CTLA-4) immune response migration T-cell During...
Articles
Biochem Soc Trans (2006) 34 (6): 1028–1031.
Published: 25 October 2006
...P.J. Murray IL-1O (interleukin-10) negatively regulates inflammation through a mechanism that blocks the expression of pro-inflammatory genes encoding cytokines, chemokines, cell-surface molecules and other molecules required for the full activation of the innate and adaptive immune responses...
Articles
Biochem Soc Trans (2006) 34 (6): 1002–1004.
Published: 25 October 2006
... 2006 © 2006 The Biochemical Society 2006 CC chemokine D6 immune response inflammation leucocyte lymphatic endothelium CCL21 CC chemokine ligand 21 CCR CC chemokine receptor DC dendritic cell GAG glycosaminoglycan References 1 Rot A. von...
Articles
Biochem Soc Trans (2006) 34 (6): 1009–1013.
Published: 25 October 2006
... in vivo , as mice lacking D6 show exaggerated cutaneous inflammatory responses and an increased susceptibility to the development of skin cancer. CCX-CKR, on the other hand, is predicted to modulate homoeostatic lymphocyte and dendritic cell trafficking, key migratory events in acquired immune responses...
Articles
Biochem Soc Trans (2003) 31 (3): 637–642.
Published: 01 June 2003
...S. Akira; M. Yamamoto; K. Takeda Toll-like receptors (TLRs) play a critical role in the detection of invading pathogens within the body and the subsequent immune response. Individual TLRs recognize distinct microbial components. The TLRs are a type 1 transmembrane receptor that possess...