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Keywords: hypertrophy
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Biochem Soc Trans (2012) 40 (1): 287–289.
Published: 19 January 2012
... into the role of PKD in hypertrophic signalling pathways. 1 To whom correspondence should be addressed (email y.sin.1@research.gla.ac.uk ). 14 7 2011 © The Authors Journal compilation © 2012 Biochemical Society 2012 fetal gene programme histone deacetylase 5 (HDAC5) hypertrophy...
Biochem Soc Trans (2010) 38 (2): 471–475.
Published: 22 March 2010
... that the synapses that were visualized as the animal progressed to end-stage disease were undergoing hypertrophy. Similar findings in samples from AD (Alzheimer's disease) patients, aged and senile individuals, and animal models of neurodegenerative diseases suggest synaptic swelling as synaptic loss is initiated...
Biochem Soc Trans (2008) 36 (6): 1354–1358.
Published: 19 November 2008
... emerin Emery–Dreifuss muscular dystrophy (EDMD) hypertrophy lamin A/C At the NE (nuclear envelope), multiprotein complexes exist that function to maintain nuclear integrity, regulate gene transcription and DNA replication. The composition of these protein complexes appears to be cell-type...
Biochem Soc Trans (2007) 35 (5): 1314–1316.
Published: 25 October 2007
... be addressed (email m.g.mackenzie@dundee.ac.uk ). 6 7 2007 © The Authors Journal compilation © 2007 Biochemical Society 2007 hypertrophy mammalian target of rapamycin (mTOR) protein degradation protein synthesis resistance exercise vacuolar protein sorting mutant 34 (Vps34...
Biochem Soc Trans (2006) 34 (2): 228–231.
Published: 20 March 2006
... of phenotypic remodelling during hypertrophy. The increase in Ca 2+ that drives the larger contractions may be responsible for switching on a second process of signalosome remodelling to down-regulate the Ca 2+ signalling pathway. It is a change in the properties of the Ca 2+ transient that seems to carry...
Biochem Soc Trans (2004) 32 (2): 383–386.
Published: 01 April 2004
... (GPCR) heart disease hypertrophy phosphoinositide 3-kinase γ (PI3Kγ) Abbreviations used: β-AR, β-adrenergic receptor; GPCR, G-protein-coupled receptor; PAF, platelet-activating factor; PI3K, phosphoinositide 3-kinase; PKB, protein kinase B; PTEN, phosphatase and tensin homologue deleted...