... landscapes. 1 To whom correspondence should be addressed (email L.Dougan@leeds.ac.uk ). 16 10 2014 © The Authors Journal compilation © 2015 Biochemical Society 2015 energy landscape extreme environments hyperthermophile mechanical unfolding polyprotein single molecule...

... evelyne.marguet@igmors.u-psud.fr or forterre@pasteur.fr ). 2 11 2012 © The Authors Journal compilation © 2013 Biochemical Society 2013 Archaea extracellular membrane vesicle hyperthermophile nanopod nanotube oligopeptide-binding protein A (OppA) stomatin Thermococcus...

...David Prangishvili; Eugene V. Koonin; Mart Krupovic Archaeal viruses, especially viruses that infect hyperthermophilic archaea of the phylum Crenarchaeota, constitute one of the least understood parts of the virosphere. However, owing to recent substantial research efforts by several groups...

...Qunxin She; Changyi Zhang; Ling Deng; Nan Peng; Zhengjun Chen; Yun Xiang Liang Sulfolobus belongs to the hyperthermophilic archaea and it serves as a model organism to study archaeal molecular biology and evolution. In the last few years, we have focused on developing genetic systems for Sulfolobus...

... are microbial stress-response elements, although it was recently shown that knocking out all known chromosomally located TA loci in Escherichia coli did not have an impact on survival under certain types of stress. The hyperthermophilic crenarchaeon Sulfolobus solfataricus encodes at least 26 vapBC (where vap...

...; although it is a type IA topoisomerase, its reaction is ATP-dependent; and it is the only hyperthermophile-specific protein. All these features have made reverse gyrase the subject of biochemical, structural and functional studies, although they have not shed complete light on the evolution, mechanism...

... of investigations of the hyperthermophilic and acidophilic crenarchaeote Sulfolobus solfataricus have been performed in recent years. Mostly, the reactions to DNA damage caused by UV light have been analysed. Whole-genome transcriptomics have demonstrated that a UV-specific response in S. solfataricus does...

.... Johnson E. de Vries S. Schroder I. J. Bacteriol. 2001 183 5491 5495 1 To whom correspondence should be addressed (email c.s.butler@ncl.ac.uk ). 22 9 2005 © 2006 The Biochemical Society 2006 Archaeoglobus fulgidus hyperthermophile molecular modelling...

...M. Guiral; C. Aubert; M.-T. Giudici-Orticoni Aquifex aeolicus is a microaerophilic, hydrogen-oxidizing, hyperthermophilic bacterium containing three [NiFe] hydrogenases. Two of these three enzymes (one membrane-bound and one soluble) have been purified and characterized. The Aquifex hydrogenases...

...’ that is not addressed by traditional screening. 1 To whom correspondence should be addressed (e-mail dcowan@uwc.ac.za ). Thermophiles 2003, a held at University of Exeter, 15–19 September 2003 19 September 2003 © 2004 Biochemical Society 2004 biocatalyst gene discovery hyperthermophile...

...D. Leduc; S. Graziani; L. Meslet-Cladiere; A. Sodolescu; U. Liebl; H. Myllykallio The hyperthermophilic anaerobic archaeon Pyrococcus abyssi , which lacks thymidine kinase, incorporates label from extracellular uracil, but not from thymidine, into its DNA. This implies that P. abyssi must...

...M.R. Johnson; C.I. Montero; S.B. Conners; K.R. Shockley; M.A. Pysz; R.M. Kelly Although much attention has been paid to the genetic, biochemical and physiological aspects of individual hyperthermophiles, how these unique micro-organisms relate to each other and to their natural habitats must...

...H. Ahmed; B. Tjaden; R. Hensel; B. Siebers Genome data as well as biochemical studies have indicated that – as a peculiarity within hyperthermophilic Archaea – Thermoproteus tenax uses three different pathways for glucose metabolism, a variant of the reversible EMP (Embden–Meyerhof–Parnas) pathway...

...D.W. Schwartzman; C.H. Lineweaver We revisit the case for the hyperthermophilic scenario for the origin of life and the last common ancestor. Evidence includes studies of phylogenetic trees, rRNA, G and C content, hyperthermophilic proteins, correlations between maximal temperature tolerances...

...H. Walden; G. Taylor; H. Lilie; T. Knura; R. Hensel The triosephosphate isomerase of the hyperthermophilic crenarchaeum Thermoproteus tenax (TtxTIM) represents a homomeric tetramer. Unlike the triosephosphate isomerases of other hyperthermophiles, however, the association of the TtxTIM tetramers...

...J. Massant; N. Glansdorff Protection of thermolabile metabolites and coenzymes is a somewhat neglected but essential aspect of the molecular physiology of hyperthermophiles. Detailed information about the mechanisms used by thermophiles to protect these thermolabile metabolites and coenzymes...

... hyperthermophile sulphate reduction thermophile Abbreviations used: E a , activation energy; SRR, sulphate reduction rate; YSNP, Yellowstone National Park. 172 Biochemical Society Transactions (2004) Volume 32, part 2 Sulphate metabolism among thermophiles and hyperthermophiles in natural aquatic...

...: Fuselloviridae , Lipothrixviridae and Rudiviridae . They all have double-stranded DNA genomes and infect hyperthermophilic crenarchaea of the orders Sulfolobales and Thermoproteales. Representatives of the different viral families share a few homologous ORFs (open reading frames). However, about 90% of all ORFs...