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Biochem Soc Trans (2022) 50 (1): 439–446.
Published: 07 January 2022
... BY) . chronic kidney disease fibroblast growth factors heart failure hypertension phosphate small molecules Plasma phosphate (P i ) is tightly controlled in the range from 0.9 to 1.45 mmol L −1 in healthy adults [ 1 ], and requires a concerted interplay between intestinal uptake, storage/release...
Biochem Soc Trans (2020) 48 (5): 1905–1916.
Published: 14 October 2020
... trafficking, cell surface expression, and zymogen activation are expected to impair corin function. To date, CORIN variants that reduce corin activity have been identified in hypertensive patients. In addition to the heart, corin expression has been detected in non-cardiac tissues, where corin and ANP...
Biochem Soc Trans (2014) 42 (1): 108–113.
Published: 23 January 2014
...Opher Gileadi Activation of cGMP synthesis leads to vasodilation, and is an important mechanism in clinical treatment of angina, heart failure, and severe peripheral and pulmonary hypertension. The nitric oxide-responsive sGC (soluble guanylate cyclase) has been the target of recent drug discovery...
Biochem Soc Trans (2007) 35 (5): 1049–1051.
Published: 25 October 2007
... 2007 Biochemical Society 2007 aldosterone epidermal growth factor receptor (EGFR) epithelial sodium channel (ENaC) hypertension protein kinase C (PKC) protein kinase D (PKD) The mineralocorticoid hormone, aldosterone, is released into the circulation by the adrenal cortex as the final...
Biochem Soc Trans (2005) 33 (1): 213–215.
Published: 01 February 2005
... email@example.com ). 16 9 2004 © 2005 The Biochemical Society 2005 glucocorticoid hypertension metabolic syndrome obesity SGK1 serum The serum- and glucocorticoid-inducible kinase SGK1 was originally cloned as early gene induced by serum and glucocorticoids in rat...