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Keywords: hydrogen peroxide
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Articles
Biochem Soc Trans (2020) 48 (3): 745–754.
Published: 15 May 2020
... © 2020 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2020 hydrogen peroxide peroxiredoxins redox signalling thiol oxidation Hydrogen peroxide is produced as a by-product of mitochondrial respiration and an end product of many metabolic...
Articles
Biochem Soc Trans (2019) 47 (5): 1461–1469.
Published: 10 September 2019
...Mark A. Watson; Hoi-Shan Wong; Martin D. Brand Changes in mitochondrial superoxide and hydrogen peroxide production may contribute to various pathologies, and even aging, given that over time and in certain conditions, they damage macromolecules and disrupt normal redox signalling. Mitochondria...
Articles
Biochem Soc Trans (2014) 42 (4): 909–916.
Published: 11 August 2014
...Elizabeth A. Veal; Lewis E. Tomalin; Brian A. Morgan; Alison M. Day As a more selectively reactive oxygen species, H 2 O 2 (hydrogen peroxide) has been co-opted as a signalling molecule, but high levels can still lead to lethal amounts of cell damage. 2-Cys Prxs (peroxiredoxins) are ubiquitous...
Articles
Biochem Soc Trans (2014) 42 (1): 42–46.
Published: 23 January 2014
...Rachel E. Martin; Zhenbo Cao; Neil J. Bulleid Hydrogen peroxide (H 2 O 2 ) can act as a signalling molecule affecting the cell cycle as well as contributing towards the oxidative stress response. The primary target of this molecule is oxidation-sensitive cysteine residues in proteins...
Articles
Biochem Soc Trans (2008) 36 (6): 1293–1298.
Published: 19 November 2008
... correspondence should be addressed (email d.allsop@lancaster.ac.uk ). 17 6 2008 © The Authors Journal compilation © 2008 Biochemical Society 2008 amyloid hydrogen peroxide metal neurodegeneration oxidative stress reactive oxygen species The formation of extracellular deposits...
Articles
Biochem Soc Trans (2006) 34 (1): 197–199.
Published: 20 January 2006
... meningitis. Following activation, macrophages produce superoxide (O 2 − ), hydrogen peroxide (H 2 O 2 ) and nitric oxide (NO). The toxicity of O 2 − , generated using X/Xo (xanthine/xanthine oxidase), and H 2 O 2 was investigated in the presence and absence of the NO donor DEA-NONOate [2-( N , N...
Articles
Biochem Soc Trans (2005) 33 (5): 1082–1086.
Published: 26 October 2005
... and peptides associated with neurodegenerative disease can generate hydrogen peroxide, a key ROS, apparently through interactions with redox-active metal ions. Our recent results suggest that ROS are generated during the very early stages of protein aggregation, when protofibrils or soluble oligomers...
Articles
Biochem Soc Trans (2004) 32 (6): 1018–1020.
Published: 26 October 2004
... 2004 hydrogen peroxide phosphatase protein tyrosine phosphatase (PTP) reactive oxygen species (ROS) redox signalling superoxide Regulated reversible phosphorylation of proteins and other cellular molecules plays a ubiquitous role in the control of cellular behaviour. Several different...
Articles
Biochem Soc Trans (2004) 32 (3): 499–501.
Published: 01 June 2004
... shown that ascorbate can enhance apoptosis in endothelial cells in the presence of chlorinated oxidants [6]. To determine Key words: apoptosis, hydrogen peroxide, neutrophil, phosphatidylserine, vitamin C. Abbreviations used: CGD, chronic granulomatous disease; DPI, diphenyleneiodonium; PS...
Articles
Biochem Soc Trans (2003) 31 (6): 1308–1311.
Published: 01 December 2003
... be addressed (e-mail hans.nohl@vu-wien.ac.at ). 679th Meeting of the Biochemical Society held at the University of Essex, Colchester, 2–4 July 2003 4 July 2003 © 2003 Biochemical Society 2003 ATPase activity bc 1 complex glutathione hydrogen peroxide mitochondria superoxide...
Articles
Biochem Soc Trans (2001) 29 (2): 345–349.
Published: 01 May 2001
... Society 2001 gene expression hydrogen peroxide MAP kinases NADPH oxidase signal transduction MAP kinase, mitogen-activated protein kinase NF-κB, nuclear factor-κB NOH, NADPH oxidase homologue ROS, reactive oxygen species SOD, superoxide dismutase Biochemical and Biomedical Aspects...