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Keywords: human epidermal growth factor receptor 2 (HER2)
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Articles

Exploring mechanisms of acquired resistance to HER2 (human epidermal growth factor receptor 2)-targeted therapies in breast cancer

Helen Creedon, Adam Byron, Joanna Main, Larry Hayward, Teresa Klinowska, Valerie G. Brunton
Journal: Biochemical Society Transactions
Biochem Soc Trans (2014) 42 (4): 822–830.
DOI: https://doi.org/10.1042/BST20140109
Published: 11 August 2014
... compilation © 2014 Biochemical Society 2014 acquired resistance breast cancer human epidermal growth factor receptor 2 (HER2) The HER (human epidermal growth factor receptor) family, comprising HER1 [more commonly referred to as EGFR (epidermal growth factor receptor)], HER2, HER3 and HER4...
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A role for the pseudokinase HER3 in the acquired resistance against EGFR- and HER2-directed targeted therapy

Jeroen Claus, Gargi Patel, Tony Ng, Peter J. Parker
Journal: Biochemical Society Transactions
Biochem Soc Trans (2014) 42 (4): 831–836.
DOI: https://doi.org/10.1042/BST20140043
Published: 11 August 2014
...- and HER2-targeted therapies, particularly in a combinatorial setting with existing therapeutic intervention. cancer drug resistance epidermal growth factor receptor (EGFR) human epidermal growth factor receptor 2 (HER2) human epidermal growth factor receptor 3 (HER3) kinase inhibition...
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