...). In the present review, we provide diverse illustrations of the use of pluripotent stem cells in drug discovery and predictive toxicology, using either human embryonic stem cell lines or iPSC lines. 1 To whom correspondence should be addressed (email mpeschanski@istem.fr ). 11 1 2010 ©...

...Peter Burton; David R. Adams; Achamma Abraham; Robert W. Allcock; Zhong Jiang; Angela McCahill; Jane Gilmour; John McAbney; Nicole M. Kane; George S. Baillie; Fergus R. McKenzie; Andrew H. Baker; Miles D. Houslay; Joanne C. Mountford; Graeme Milligan hESCs (human embryonic stem cells) offer great...

... cardiomyocytes, namely those from hPSCs [human PSCs (pluripotent stem cells)], and place particular emphasis on the pharmacological responses that have been reported. hPSCs comprise hESCs (human embryonic stem cells), derived from the blastocyst stage embryo [ 6 ], and hiPSCs (human induced PSCs) derived...

.... Thus, if cell therapy should be widely available, it will require an unlimited source of cells to serve as a ‘biological’ insulin pump. At this time, the development of β-cells from hESCs (human embryonic stem cells) has emerged as the most attractive alternative. It is envisioned that ultimate success...