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Keywords: histone mutationClose
Journal: Biochemical Society Transactions
Biochem Soc Trans (2022) 50 (2): 907–919.
Published: 31 March 2022
... in histone coding genes, including some that map to the acidic patch. How cancer-related acidic patch histone mutations affect nucleosome remodeling is mainly unknown. Recent advances in in vitro chromatin reconstitution have enabled access to physiologically relevant nucleosomes, including asymmetric...