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Keywords: helix 5Close
Journal: Biochemical Society Transactions
Biochem Soc Trans (2013) 41 (1): 159–165.
Published: 29 January 2013
... of these occurrences, whereas partial agonists stabilize a contraction of the binding pocket but not the rotamer change of serine (5.46). It is likely that subtle changes in the interactions between transmembrane helix 5 (H5) and H3/H4 on agonist binding promote the formation of the activated state. 1...