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Keywords: heart disease
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Articles
Biochem Soc Trans (2022) 50 (5): 1247–1255.
Published: 25 October 2022
... governing fibroblast activation. A better understanding of the molecular mechanisms that trigger and sustain the fibrotic process in heart disease has the potential to accelerate the development of therapies that specifically target the cardiac activated fibroblasts, which are at the moment unavailable...
Articles
Biochem Soc Trans (2020) 48 (1): 165–177.
Published: 03 February 2020
... The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2020 caveolae caveolin heart disease metabolism mitochondria Mitochondria are classically known as the ‘powerhouse’ of the cell, sustaining high energy needs through oxidative phosphorylation...
Articles
Biochem Soc Trans (2007) 35 (5): 957–961.
Published: 25 October 2007
... or contractility give rise to pathological consequences. Indeed, heart disease is a significant cause of mortality, being responsible, in 2004, for 137700 deaths in the U.K., equating to 24% of all deaths [ 1 ]. These statistics surpass the 33000 deaths a year from lung cancer, 16000 deaths from colorectal cancer...
Articles
Biochem Soc Trans (2004) 32 (2): 383–386.
Published: 01 April 2004
... (GPCR) heart disease hypertrophy phosphoinositide 3-kinase γ (PI3Kγ) Abbreviations used: β-AR, β-adrenergic receptor; GPCR, G-protein-coupled receptor; PAF, platelet-activating factor; PI3K, phosphoinositide 3-kinase; PKB, protein kinase B; PTEN, phosphatase and tensin homologue deleted...
Articles
Biochem Soc Trans (1999) 27 (4): 459–463.
Published: 01 August 1999
...(a) CHD, coronary heart disease Lp(a). lipoprotein(a) WOSCOPS, Wed of Scotland Coronary Prevention Study Lipoprotein(a) : the Really Bad Cholesterol? Use of the West of Scotland Coronary Prevention Study bio-bank to provide new insights into the control of plasma lipoprotein(a) concentrations...