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Keywords: guanine-nucleotide-exchange factor (GEF)
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Articles
Biochem Soc Trans (2014) 42 (1): 89–97.
Published: 23 January 2014
... endothelial barrier function exchange protein directly activated by cAMP (Epac) guanine-nucleotide-exchange factor (GEF) protein kinase A (PKA) vascular smooth muscle vasculature vasodilatation The second messenger cAMP controls a range of vascular processes, including endothelial barrier...
Articles
Biochem Soc Trans (2014) 42 (1): 201–205.
Published: 23 January 2014
... of the polarity pathways, analogies between fission yeast and other model systems can be useful to decipher how cells can actively define their shape by polarized growth. Cdc42 cytoskeleton GTPase-activating protein (GAP) guanine-nucleotide-exchange factor (GEF) morphogenesis polarized growth secretion...
Articles
Biochem Soc Trans (2012) 40 (6): 1421–1425.
Published: 21 November 2012
...-exchange factor (GEF) Rab Rab membrane receptor vesicular trafficking The Rab family of small Ras-like G-proteins, consisting of 11 members in yeast and more than 60 in humans, are key regulators of intracellular vesicular trafficking in eukaryotic cells (for a recent review of Rab proteins, see...
Articles
Biochem Soc Trans (2012) 40 (6): 1337–1347.
Published: 21 November 2012
... be important in defining competing trafficking events involving different Rab proteins. 1 To whom correspondence should be addressed (email m.mccaffrey@ucc.ie ). 14 8 2012 © 2012 The Authors Journal 2012 disease GTPase-activating protein (GAP) guanine-nucleotide-exchange factor...
Articles
Biochem Soc Trans (2012) 40 (6): 1373–1377.
Published: 21 November 2012
...) guanine-nucleotide-dissociation inhibitor (GDI) Golgi complex GTPase-activating protein (GAP) guanine-nucleotide-exchange factor (GEF) Rab GTPase Highlights of the new ‘cisternal progenitor model’ are be summarized in this section. The Golgi comprises a series of flattened cisterna that link...
Articles
Biochem Soc Trans (2012) 40 (5): 1074–1079.
Published: 19 September 2012
... on LRRK2's kinase activity, the present review focuses on the function of LRRK2's GTPase activity in LRRK2 physiology and pathophysiology. © The Authors Journal compilation © 2012 Biochemical Society 2012 GTPase-activating protein (GAP) guanine-nucleotide-exchange factor (GEF) GTPase kinase...
Articles
Biochem Soc Trans (2010) 38 (5): 1235–1241.
Published: 24 September 2010
... correspondence should be addressed (email boris.kholodenko@ucd.ie ). 10 3 2010 © The Authors Journal compilation © 2010 Biochemical Society 2010 gradient pattern GTPase-activating protein (GAP) guanine-nucleotide-exchange factor (GEF) phosphorylation wave signalling In the middle...
Articles
Biochem Soc Trans (2008) 36 (4): 658–664.
Published: 22 July 2008
... The Authors Journal compilation © 2008 Biochemical Society 2008 childhood ataxia with central nervous system hypomyelination (CACH) eukaryotic initiation factor 2B (eIF2B) G-protein guanine-nucleotide-exchange factor (GEF) leukoencephalopathy with vanishing white matter (VWM) translation initiation...