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Keywords: glyoxal
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Biochem Soc Trans (2014) 42 (2): 504–510.
Published: 20 March 2014
...Paul J. Thornalley; Naila Rabbani Methylglyoxal and glyoxal are endogenous α-oxoaldehyde metabolites and substrates of the glyoxalase system. These and related α-oxoaldehydes are often determined in cell, tissue and body fluid samples by derivatization with 1,2-diaminobenzene and similar compounds...
Biochem Soc Trans (2003) 31 (6): 1390–1393.
Published: 01 December 2003
...N. Shangari; W.R. Bruce; R. Poon; P.J. O'Brien Glyoxals are reactive α-oxoaldehydes that are formed endogenously from sugars, the levels of which are increased in various pathological conditions associated with hyperglycaemia and thiamine deficiency. However, the molecular cytotoxic mechanisms...